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![3,8-Diazabicyclo[3.2.1]octanes and their use in the treatment of cardiac arrhythmias](/abs-image/US/2006/03/14/US07012074B2/abs.jpg.150x150.jpg)
1.发明授权3,8-Diazabicyclo[3.2.1]octanes and their use in the treatment of cardiac arrhythmias 失效3,8-二氮杂双环[3.2.1]辛烷及其在心律失常治疗中的应用公开(公告)号：US07012074B2
公开(公告)日：2006-03-14
申请号：US10399663
申请日：2001-10-18
申请人： Magnus Bjorsne , Kurt-Jürgen Hoffmann , Fritiof Pontén , Gert Strandlund , Peder Svensson , Michael Wilstermann
发明人： Magnus Bjorsne , Kurt-Jürgen Hoffmann , Fritiof Pontén , Gert Strandlund , Peder Svensson , Michael Wilstermann
IPC分类号： A01N43/58
CPC分类号： C07D487/08 , A61K31/495
摘要： There is provided compounds of formula (I), wherein R1, R2 and Ra to Rb have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.
摘要翻译： 提供了式（I）的化合物，其中R 1，R 2和R 2至R b， 具有描述中给出的含义，其可用于预防和治疗心律失常，特别是心房和室性心律失常。
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公开(公告)号：US07351821B2
公开(公告)日：2008-04-01
申请号：US11640417
申请日：2006-12-18
申请人： Annika Björe , Magnus Björsne , David Cladingboel , Kurt-Jürgen Hoffmann , John Pavey , Fritiof Pontén , Gert Strandlund , Peder Svensson , Colin Thomson , Michael Wilsterman
发明人： Annika Björe , Magnus Björsne , David Cladingboel , Kurt-Jürgen Hoffmann , John Pavey , Fritiof Pontén , Gert Strandlund , Peder Svensson , Colin Thomson , Michael Wilsterman
IPC分类号： C07D265/36 , C07D498/02
CPC分类号： C07D498/08
摘要： There is provided compounds of formula I, wherein R1, R2, R3, R4, R41 to R46, A, B and G have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.
摘要翻译： 提供式I化合物，其中R 1，R 2，R 3，R 4，R 4，R 4， A，B和G具有描述中给出的含义，其可用于预防和治疗心律失常，特别是心房和室性心律失常 。
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3.发明授权公开(公告)号：US06559143B1
公开(公告)日：2003-05-06
申请号：US09688251
申请日：2000-10-16
申请人： Annika Björe , Magnus Björsne , Kurt-Jürgen Hoffmann , Fritiof Pontén , Gert Strandlund , Peder Svensson , Michael Wilsterman
发明人： Annika Björe , Magnus Björsne , Kurt-Jürgen Hoffmann , Fritiof Pontén , Gert Strandlund , Peder Svensson , Michael Wilsterman
IPC分类号： A61K31535
CPC分类号： C07D498/08
摘要： There is provided compounds of formula I, wherein R1, R2, R3, R4, R41 to R46, A, B and G have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.
摘要翻译： 提供式I化合物，其中R 1，R 2，R 3，R 4，R 41至R 46，A，B和G具有描述中给出的含义，其可用于预防和治疗心律失常，特别是心房和 室性心律失常。
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![3,7-diazabicyclo[3.3.0]octanes and their use in the treatment of cardiac arrhythmias](/abs-image/US/2006/12/05/US07144914B2/abs.jpg.150x150.jpg)
4.发明授权3,7-diazabicyclo[3.3.0]octanes and their use in the treatment of cardiac arrhythmias 失效3,7-二氮杂双环[3.3.0]辛烷及其在心律失常治疗中的应用公开(公告)号：US07144914B2
公开(公告)日：2006-12-05
申请号：US10467043
申请日：2002-01-29
IPC分类号： A61K31/407 , C07D487/02
CPC分类号： C07D487/04
摘要： There is provided compounds of formula (I) wherein R1 to R4, Ra to Rf, A and B have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.
摘要翻译： 提供式（I）化合物，其中R 1至R 4，R a至R f，R f， A和B具有描述中给出的含义，其可用于预防和治疗心律失常，特别是心房和心室心律失常。
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5.发明授权公开(公告)号：US06559162B2
公开(公告)日：2003-05-06
申请号：US09763892
申请日：2001-02-28
IPC分类号： A61K31439
CPC分类号： C07D221/24
摘要： Compounds of formula I, wherein R1, R2, R3 and Ra Rh are as defined in the specification. The compounds are useful in the prophylaxis and in the treatment of arrhythmias, in particular a trial and ventricular arrhythmias.
摘要翻译： 式I的化合物，其中R 1，R 2，R 3和R a Rh如说明书中所定义。 这些化合物可用于预防和治疗心律不齐，特别是试验和室性心律失常。
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