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公开(公告)号:US20090202520A1
公开(公告)日:2009-08-13
申请号:US12215700
申请日:2008-06-27
申请人: Mark L. Lupher, JR. , Teresa Surowy , Shawn Li
发明人: Mark L. Lupher, JR. , Teresa Surowy , Shawn Li
IPC分类号: A61K39/395 , C12Q1/00 , A61K38/00 , A61K31/7088
CPC分类号: C07K14/4737 , G01N33/6887 , G01N2333/4709 , G01N2333/4737 , G01N2800/085 , G01N2800/382
摘要: Compositions and methods are provided for the treatment of fibrosis related disorders utilizing the ratio of the concentration of serum amyloid P(SAP) to C-reactive protein (CRP) in a patient. The methods may further comprise determining the R131/H131 polymorphism of FcγRIIA. Diagnostic methods are also provided.
摘要翻译: 提供了使用患者血清淀粉样蛋白P(SAP)与C反应蛋白(CRP)浓度之比来治疗纤维化相关疾病的组合物和方法。 所述方法还可以包括确定FcγRIIA的R131 / H131多态性。 还提供了诊断方法。