公开(公告)号：US07183069B2

公开(公告)日：2007-02-27

申请号：US10383007

申请日：2003-03-06

申请人： Masaki Yamaguchi ,  Hiroshi Yoshida ,  Nobutaka Kusaba ,  Yasufumi Mizuno

发明人： Masaki Yamaguchi ,  Hiroshi Yoshida ,  Nobutaka Kusaba ,  Yasufumi Mizuno

IPC分类号： C12Q1/40

CPC分类号： G01N33/52 ,  C12Q1/40

摘要： An object of the present invention is to provide a means for measuring amylase activity existing in biological samples such as saliva in a more convenient manner and is particularly to provide a means (reagent for measurement, method for measurement and apparatus) by which a sample containing high concentrations of amylase is measured. There has been found a means (reagent for measurement, method for measurement and apparatus), whereby amylase activity in an amylase sample having a high activity value can be quite conveniently measured by making an oligosaccharide substrate carry on a support in an enzymatic method for measuring amylase activity using a modified oligosacharide substrate, whereupon the present invention has been achieved.

摘要翻译： 本发明的目的是提供一种用于以更方便的方式测量存在于生物样品例如唾液中的淀粉酶活性的方法，并且特别地提供一种用于测量的装置（测量方法，测量方法和装置），通过该装置 测量高浓度的淀粉酶。 已经发现了一种方法（用于测量的试剂，测量方法和装置），其中具有高活性值的淀粉酶样品中的淀粉酶活性可以通过使寡糖底物在酶法测量中进行支持而非常方便地测量 使用改性的寡糖基底的淀粉酶活性，从而实现了本发明。