专利检索 ap:("Masao Koyama" OR "Chika Kikuchi" OR "Osamu Ushiroda" OR "Takashi Ando" OR "Hiroshi Nagaso" OR "Kazuyuki Fuji" OR "Masayo Okuno" OR "Toyokazu Hiranuma") AND inv:"Masayo Okuno" 第 1 页

1.

发明授权
Tetrahydrobenzindole compounds 有权
标题翻译：四氢苯并吲哚化合物

公开(公告)号：US06355642B1

公开(公告)日：2002-03-12

申请号：US09214114

申请日：1998-12-28

申请人： Masao Koyama , Chika Kikuchi , Osamu Ushiroda , Takashi Ando , Hiroshi Nagaso , Kazuyuki Fuji , Masayo Okuno , Toyokazu Hiranuma

发明人： Masao Koyama , Chika Kikuchi , Osamu Ushiroda , Takashi Ando , Hiroshi Nagaso , Kazuyuki Fuji , Masayo Okuno , Toyokazu Hiranuma

IPC分类号： A61K3140

CPC分类号： C07D401/06 , C07D209/92 , C07D401/12 , C07D403/12

摘要： A compound of formula (I) for use in the treatment or prevention of mental diseases A is N, CH, C having a double bond or CR5; each of B and Z is independently N, CH or CR1, with the proviso that A is N when B and/or Z is N; R1, R2, R3, R4 and R5 and n are as defined in the specification.

摘要翻译： 用于治疗或预防精神疾病的式（I）化合物A是具有双键的N，CH，C或CR5; B和Z各自独立地为N，CH或CR1，条件是当B和/或Z为N时A为N; R1，R2，R3，R4和R5以及n如说明书中所定义。

2.

发明授权
Tetrahydrobenzindole derivatives 失效
标题翻译：四氢苯并吲哚衍生物

公开(公告)号：US06498251B1

公开(公告)日：2002-12-24

申请号：US09582416

申请日：2001-03-08

申请人： Chika Kikuchi , Takashi Ando , Kazuyuki Fuji , Masayo Okuno , Eriko Morita , Masako Imai , Osamu Ushiroda , Masao Koyama , Toyokazu Hiranuma

发明人： Chika Kikuchi , Takashi Ando , Kazuyuki Fuji , Masayo Okuno , Eriko Morita , Masako Imai , Osamu Ushiroda , Masao Koyama , Toyokazu Hiranuma

IPC分类号： C07D20990

CPC分类号： C07D401/06 , C07D209/92 , C07D405/12 , C07D471/04 , C07D487/04

摘要： Compounds containing tetrahydrobenzindole which bind to serotonin receptor and are useful in treatment or prevention of disease induced by abnormality of central peripheral serotonin controlling functions.

摘要翻译： 含有与5-羟色胺受体结合的四氢苯并吲哚的化合物，可用于治疗或预防由中枢外周血清素控制功能异常引起的疾病。

3.

发明授权
Optically active tetrahydrobenzindole derivative 失效
标题翻译：光活性四氢苯并吲哚衍生物

公开(公告)号：US06407112B1

公开(公告)日：2002-06-18

申请号：US09673833

申请日：2000-10-23

申请人： Masao Koyama , Osamu Ushiroda , Chika Kikuchi , Takashi Ando , Eriko Morita , Masayo Okuno , Toyokazu Hiranuma

发明人： Masao Koyama , Osamu Ushiroda , Chika Kikuchi , Takashi Ando , Eriko Morita , Masayo Okuno , Toyokazu Hiranuma

IPC分类号： C07D20992

CPC分类号： C07D471/04 , C07D209/92 , C07D491/04 , C07D495/04

摘要： Optically active tetrahydrobenzindole type compounds having affinity for a 5-HT receptor, useful for prevention and treatment of mental diseases. A species compound is (S)-2a-4-(4-(2-methoxyphenyl)piperazinyl)butyl)-2a,3,4,5,-tetrahydro 1 H-benz[cd]indol-2-one.

摘要翻译： 对5-HT受体具有亲和力的光学活性四氢苯并吲哚型化合物，可用于预防和治疗精神疾病。化合物为（S）-2a-4-（4-（2-甲氧基苯基）哌嗪基）丁基）-2a，3,4,5， - 四氢-1H-苯并[cd]吲哚-2-酮。