公开(公告)号：US20100076040A1

公开(公告)日：2010-03-25

申请号：US12444630

申请日：2007-10-05

申请人： Mathias KRULL

发明人： Mathias KRULL

IPC分类号： C07D413/02 ,  A61K31/421

CPC分类号： C07D263/62 ,  C07D263/64 ,  C07D413/06 ,  C07D413/10

摘要： The invention relates to a method for producing bisbenzoxazoles that are interconnected by means of a system of conjugated double bonds, according to which o-aminophenols are reacted with dicarboxylic acids, the carboxyl groups of which are interconnected via a double bond or a system of conjugated double bonds, to form an ammonium salt, said ammonium salt being converted in the presence of dehydrogenating catalysts and solvents with a low dielectric loss into benzoxazol by means of microwave radiation.

摘要翻译： 本发明涉及一种通过共轭双键体系相互连接的双苯并恶唑的方法，根据该方法，邻氨基苯酚与二羧酸反应，二羧酸通过双键或共轭体系互连 双键形成铵盐，所述铵盐在脱氢催化剂和低介电损耗的溶剂存在下通过微波辐射转化成苯并恶唑。