公开(公告)号：US11883540B2

公开(公告)日：2024-01-30

申请号：US17320446

申请日：2021-05-14

Applicant: McMaster University

Inventor： Todd Hoare ,  Jonathan Dorogin ,  David Koff ,  Andrew Singh

IPC: A61K9/50 ,  A61K9/00

CPC classification number: A61K9/5031 ,  A61K9/0009 ,  A61K9/501

Abstract: The present application relates to a vehicle whose shell material is modified with at least one additional secondary phase that acts as a cork. In the presence of an energy source (preferably ultrasound), the corks embedded in the shell are either removed from the shell to create permanent pores or perturbed within the shell to create transient pores that can control transport in or out of the vehicle.

公开(公告)号：US20210353550A1

公开(公告)日：2021-11-18

申请号：US17320446

申请日：2021-05-14

Applicant: McMaster University

Inventor： Todd Hoare ,  Jonathan Dorogin ,  David Koff ,  Andrew Singh

IPC: A61K9/50 ,  A61K9/00

Abstract: The present application relates to a vehicle whose shell material is modified with at least one additional secondary phase that acts as a cork. In the presence of an energy source (preferably ultrasound), the corks embedded in the shell are either removed from the shell to create permanent pores or perturbed within the shell to create transient pores that can control transport in or out of the vehicle.