公开(公告)号：US20160317454A1

公开(公告)日：2016-11-03

申请号：US14826328

申请日：2015-08-14

Applicant: Medical And Pharmaceutical Industry Technology And Development Center

Inventor： Chih-Chiang YANG ,  Yuan-Chih LE ,  Yu-Liang LIN ,  Yi-Ming LIOU

IPC: A61K9/50 ,  A61K9/48 ,  A61K31/403

CPC classification number: A61K9/5042 ,  A61K9/5026 ,  A61K9/5078 ,  A61K9/5089 ,  A61K31/403

Abstract: A controlled release pharmaceutical composition is disclosed, which comprises: a drug core comprising 10-50 mg of Carvedilol or a pharmaceutical acceptable salt thereof, and a first pharmaceutical acceptable polymer, wherein a content of the first pharmaceutical acceptable polymer is 0.01-50% based on a total weight of the drug core; and a controlled release coating layer covering the drug core and comprising a second pharmaceutical acceptable polymer. In addition, a method for manufacturing the aforementioned controlled release pharmaceutical composition is also disclosed.

Abstract translation: 公开了一种控释药物组合物，其包含：包含10-50mg卡维地洛或其药学上可接受的盐的药物核心和第一药学上可接受的聚合物，其中第一药学上可接受的聚合物的含量为0.01-50％ 药物核心总重量; 以及覆盖药物核心并包含第二药学上可接受的聚合物的控释层。 此外，还公开了制造上述控释药物组合物的方法。