公开(公告)号：US11083889B2

公开(公告)日：2021-08-10

申请号：US15884636

申请日：2018-01-31

Applicant: Medtronic, Inc.

Inventor： Zhongping Yang ,  Andrea Asleson ,  Gonzalo Martinez ,  Rick D. McVenes ,  Christopher W. Storment

IPC: A61N1/05 ,  A61N1/365 ,  A61N1/375

Abstract: An implantable medical lead having an elongated lead body extending from a proximal end to a distal end, at least one conductor extending within the lead body from the proximal end to the distal end, and a fixation member having a proximal end and a distal end, the proximal end of the electrode configured to be electrically coupled to the distal end of the lead body. The fixation member includes a first delivery port and a second delivery port for releasing a therapeutic agent from the fixation member to tissue of a patient, wherein the first delivery port is positioned along the proximal end of the fixation member to deliver the therapeutic agent to endothelial cells along an endothelial layer of tissue, and the second delivery port is positioned along the distal end of the fixation member and spaced a distance from the first delivery port to deliver the therapeutic agent to myocardial tissue within a myocardial layer of the tissue, and wherein no delivery ports are positioned within the distance that the second delivery port is spaced from the first delivery port.

公开(公告)号：US20190232053A1

公开(公告)日：2019-08-01

申请号：US15884636

申请日：2018-01-31

Applicant: Medtronic, Inc.

Inventor： Zhongping Yang ,  Andrea Asleson ,  Gonzalo Martinez ,  Rick D. McVenes ,  Christopher W. Storment

IPC: A61N1/05 ,  A61N1/375 ,  A61N1/365

CPC classification number: A61N1/0575 ,  A61N1/365 ,  A61N1/37512 ,  A61N1/3756

Abstract: An implantable medical lead having an elongated lead body extending from a proximal end to a distal end, at least one conductor extending within the lead body from the proximal end to the distal end, and a fixation member having a proximal end and a distal end, the proximal end of the electrode configured to be electrically coupled to the distal end of the lead body. The fixation member includes a first delivery port and a second delivery port for releasing a therapeutic agent from the fixation member to tissue of a patient, wherein the first delivery port is positioned along the proximal end of the fixation member to deliver the therapeutic agent to endothelial cells along an endothelial layer of tissue, and the second delivery port is positioned along the distal end of the fixation member and spaced a distance from the first delivery port to deliver the therapeutic agent to myocardial tissue within a myocardial layer of the tissue, and wherein no delivery ports are positioned within the distance that the second delivery port is spaced from the first delivery port.