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公开(公告)号:US20120135483A1
公开(公告)日:2012-05-31
申请号:US13303887
申请日:2011-11-23
申请人: Melanie Bonnekessel , Kalus Ditrich , Jurgen Dauwel , Achim Sorg , Wolfgang Ladner , Bryan Cooper , Rene Backes
发明人: Melanie Bonnekessel , Kalus Ditrich , Jurgen Dauwel , Achim Sorg , Wolfgang Ladner , Bryan Cooper , Rene Backes
CPC分类号: C12P7/02 , C12N9/20 , C12N11/14 , C12P41/004
摘要: The present invention relates to the preparation of isomerically pure substituted cyclohexanols starting from a mixture of cis/trans substituted cyclohexanols which comprises reacting the cis/trans mixture of a substituted cyclohexanol with a dicarboxylic acid anhydride in the presence of a lipase, to give the trans semi-ester which is separated off from the unreacted substituted cyclohexanol cis isomer.
摘要翻译: 本发明涉及从顺式/反式取代的环己醇的混合物开始制备异构纯的取代的环己醇,其包括在脂肪酶存在下使取代的环己醇的顺式/反式混合物与二羧酸酐反应,得到反式 与未反应的取代的环己醇顺式异构体分离的半酯。