公开(公告)号：US20240025912A1

公开(公告)日：2024-01-25

申请号：US18318760

申请日：2023-05-17

申请人： Merck Sharp & Dohme LLC

发明人： Joanna L. Chen ,  Yi-Heng Chen ,  Erin F. DiMauro ,  Min Liu ,  Joey L. Methot ,  Andrew J. Musacchio ,  Anandan Palani ,  Barbara Pio ,  Lorena Rico Duque ,  Phieng Siliphaivanh ,  Brandon A. Vara

IPC分类号： C07D487/04 ,  C07D513/04 ,  C07D498/04

CPC分类号： C07D487/04 ,  C07D498/04 ,  C07D513/04

摘要： Described herein are compounds of Formula I




or a pharmaceutically acceptable salt thereof. The compounds of Formula I act as RIPK1 inhibitors and can be useful in preventing, treating or acting as a remedial agent for RIPK1-related diseases.