公开(公告)号：US20240369558A1

公开(公告)日：2024-11-07

申请号：US18580427

申请日：2022-07-21

Applicant: Mercy Bioanalytics, Inc.

Inventor： Joseph Charles Sedlak ,  Emily Susan Winn-Deen ,  Daniel Gusenleitner ,  Anthony David Couvillon ,  laura Teresa Bortolin ,  Daniel Parker Salem ,  Kelly Biette ,  Ibukunoluwapo O. Zabroski

IPC: G01N33/574 ,  C12Q1/6886

Abstract: The present disclosure in one aspect provides technologies for detection of breast cancer, e.g., early detection of breast cancer. In another aspect, technologies provided herein are useful for selecting and/or monitoring and/or evaluating efficacy of, a treatment administered to a subject determined to have or susceptible to breast cancer. In some embodiments, technologies provided herein are useful for development of companion diagnostics, e.g., by measuring tumor burdens and changes in tumor burdens in conjunction with therapeutics. In some embodiments, technologies provided herein are useful for development of companion diagnostics, e.g., by identifying biomarkers in subjects' bodily fluid samples (e.g., blood samples) that are associated with therapeutic response.