公开(公告)号：US20230313308A1

公开(公告)日：2023-10-05

申请号：US17713143

申请日：2022-04-04

Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH ,  Singapore Health Services Pte Ltd ,  National University Hospital (Singapore) Pte Ltd ,  Tan Tock Seng Hospital Pte Ltd ,  MiRXES Lab Pte. Ltd.

Inventor： Siew Gek Lee-Lim ,  Ruiyang Zou ,  Lihan Zhou ,  He Cheng ,  Bo Anders Mikael Hartman ,  Heng-Phon Too

IPC: C12Q1/6886

CPC classification number: C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/178 ,  C12Q2600/158 ,  C12Q2600/118

Abstract: This technology relates to a method of treating breast cancer in a subject and a method of determining whether a breast lesion in a subject is malignant or benign using miRNA panels.

公开(公告)号：US20220186320A1

公开(公告)日：2022-06-16

申请号：US17594805

申请日：2020-04-14

Applicant: MiRXES Lab Pte. Ltd.

Inventor： Ruiyang Zou

IPC: C12Q1/6886

Abstract: The present invention relates to the field of molecular biology. Disclosed are a miRNA marker combination and a kit for diagnosing gastric cancer. The miRNA marker combination for diagnosing gastric cancer includes at least four markers selected from: hsa-miR-29c-3p, hsa-miR-424-5p, hsa-miR-103a-3p, hsa-miR-93-5p, hsa-miR-181a-5p, hsa-miR-21-5p, hsa-miR-140-5p, hsa-miR-30e-5p, hsa-miR-142-5p, hsa-miR-126-3p, hsa-miR-183-5p and hsa-miR-340-5p. The marker combination for diagnosing gastric cancer can be used to distinguish blood serum of a patient with gastric cancer from that of a Healthy human. The diagnostic kit of the present invention can diagnosis gastric cancers easily, effectively and non-invasively.