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公开(公告)号:US06245539B1
公开(公告)日:2001-06-12
申请号:US09167299
申请日:1998-10-06
IPC分类号: C12N900
CPC分类号: C12N9/93 , C07K16/40 , C12Y601/01022
摘要: The CDNA sequence of human cytosolic asparaginyl-tRNA synthesis AsnRS, the bacterial expression of the recombinant enzyme and its activity assays with different sources of tRNA is described. The reactivity with a human autoimmune serum is described. The implication of the human cytoplasmic AsnRS in an autoimmune disorder is a property of this enzyme.
摘要翻译: 描述了人类胞质内天冬酰胺酰-tRNA合成AsnRS的CDNA序列,重组酶的细菌表达及其具有不同来源的tRNA的活性测定。 描述了与人自身免疫血清的反应性。 人类细胞质AsnRS在自身免疫性疾病中的含义是该酶的特性。