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公开(公告)号:US5776465A
公开(公告)日:1998-07-07
申请号:US461725
申请日:1995-06-05
IPC分类号: A61K38/00 , A61K39/00 , A61K39/04 , C07K14/16 , C07K14/35 , C07K14/52 , C07K14/55 , C12N1/21 , C12N15/74 , C12N15/87 , A61K45/05
CPC分类号: A61K39/04 , C07K14/005 , C07K14/35 , C07K14/52 , C07K14/55 , C12N15/74 , C12N15/87 , C12R1/32 , A61K38/00 , A61K39/00 , C12N2740/16022 , C12N2740/16122 , C12N2740/16222 , Y10S435/863 , Y10S435/864 , Y10S435/865 , Y10S435/866
摘要: The present invention relates to recombinant mycobacteria, particularly recombinant M. bovis BCG, which express heterologous DNA encoding a product (protein or polypeptide) of interest, such a protein or polypeptide (e.g., an antigen) against which an immune response is desired, or a cytokine.
摘要翻译: 本发明涉及重组分枝杆菌,特别是重组牛分枝杆菌BCG,其表达编码目标产物(蛋白质或多肽)的异源DNA,例如需要免疫应答的蛋白质或多肽(例如抗原),或 一种细胞因子。
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公开(公告)号:US5591632A
公开(公告)日:1997-01-07
申请号:US96027
申请日:1993-07-22
IPC分类号: A61K38/00 , A61K39/00 , A61K39/04 , C07K14/16 , C07K14/35 , C07K14/52 , C07K14/55 , C12N1/21 , C12N15/74 , C12N15/87
CPC分类号: A61K39/04 , C07K14/005 , C07K14/35 , C07K14/52 , C07K14/55 , C12N15/74 , C12N15/87 , C12R1/32 , A61K38/00 , A61K39/00 , C12N2740/16022 , C12N2740/16122 , C12N2740/16222 , Y10S435/863 , Y10S435/864 , Y10S435/865 , Y10S435/866
摘要: The present invention relates to recombinant mycobacteria, particularly recombinant M. bovis BCG, which express heterologous DNA encoding a product (protein or polypeptide) of interest, such a protein or polypeptide (e.g., an antigen) against which an immune response is desired or a cytokine.
摘要翻译: 本发明涉及重组分枝杆菌,特别是重组牛分枝杆菌BCG,其表达编码感兴趣的产物(蛋白质或多肽)的异源DNA,例如期望免疫应答的蛋白质或多肽(例如,抗原)或 细胞因子。
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