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公开(公告)号:US07276630B2
公开(公告)日:2007-10-02
申请号:US11525281
申请日:2006-09-22
IPC分类号: C07C211/00
CPC分类号: C07C227/18 , C07B37/04 , C07C229/38
摘要: A process is provided for preparing optionally substituted arylated benzylamines from the corresponding optionally substituted aryl halides and optionally substituted benzylamines using a specific solvent mixture, a base and a catalyst comprising a palladium compound and a bisaryldialkylphosphine.
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公开(公告)号:US20070073078A1
公开(公告)日:2007-03-29
申请号:US11525281
申请日:2006-09-22
IPC分类号: C07C253/30 , C07C209/10
CPC分类号: C07C227/18 , C07B37/04 , C07C229/38
摘要: A process is provided for preparing optionally substituted arylated benzylamines from the corresponding optionally substituted aryl halides and optionally substituted benzylamines using a specific solvent mixture, a base and a catalyst comprising a palladium compound and a bisaryldialkylphosphine.
摘要翻译: 提供了一种方法,用于使用特定的溶剂混合物,碱和包含钯化合物和双芳基二烷基膦的催化剂从相应的任选取代的芳基卤化物和任选取代的苄基胺制备任选取代的芳基化苄基胺。
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公开(公告)号:US20070149802A1
公开(公告)日:2007-06-28
申请号:US11525279
申请日:2006-09-22
IPC分类号: C07C229/18
CPC分类号: C07C227/18 , C07C229/38
摘要: An advantageous process is provided for preparing methyl 4-(aminomethyl)benzoate by esterifying 4-(aminomethyl)benzoic acid and subsequently obtaining the methyl 4-(aminomethyl)benzoate, this process proceeding under specific pH and temperature control and isolation of the hydrochloride of methyl 4-(aminomethyl)benzoate formed as an intermediate being avoidable.
摘要翻译: 提供通过酯化4-(氨基甲基)苯甲酸并随后得到4-(氨基甲基)苯甲酸甲酯来制备4-(氨基甲基)苯甲酸甲酯的有利方法,该方法在特定pH和温度控制下进行,并分离盐酸 形成为中间体的4-(氨基甲基)苯甲酸甲酯是可避免的。
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公开(公告)号:US07265238B2
公开(公告)日:2007-09-04
申请号:US11525279
申请日:2006-09-22
IPC分类号: C07C229/00 , C07C67/08 , C07C69/00
CPC分类号: C07C227/18 , C07C229/38
摘要: An advantageous process is provided for preparing methyl 4-(aminomethyl)benzoate by esterifying 4-(aminomethyl)benzoic acid and subsequently obtaining the methyl 4-(aminomethyl)benzoate, this process proceeding under specific pH and temperature control and isolation of the hydrochloride of methyl 4-(aminomethyl)benzoate formed as an intermediate being avoidable.
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公开(公告)号:US06462242B1
公开(公告)日:2002-10-08
申请号:US09587742
申请日:2000-06-05
IPC分类号: C07C3346
CPC分类号: C07C209/48 , C07C29/14 , C07C45/49 , C07C47/55 , C07C211/27 , C07C33/46
摘要: Benzyl alcohols, particularly those which bear fluorine substituents or fluoroalkyl substituents on the benzyl ring, can be obtained by formylation of corresponding aryl bromides to form benzaldehydes and reduction of the latter using further formate, wherein the benzaldehydes formed do not have to be isolated.
摘要翻译: 苯甲醇,特别是在苄基环上具有氟取代基或氟代烷基取代基的那些,可以通过相应的芳基溴化物的甲酰化形成苯甲醛,并使用其它甲酸酯还原后者而获得,其中形成的苯甲醛不必分离。
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