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    Apparatus for performing SERS
    1.
    发明授权
    Apparatus for performing SERS 有权
    用于执行SERS的装置

    公开(公告)号：US08462333B2

    公开(公告)日：2013-06-11

    申请号：US12905891

    申请日：2010-10-15

    申请人： Wei Wu ,  Zhiyong Li ,  Shih-Yuan Wang ,  Michael Josef Stuke ,  Lars Helge Thylen ,  Fung Suong Ou ,  Min Hu

    发明人： Wei Wu ,  Zhiyong Li ,  Shih-Yuan Wang ,  Michael Josef Stuke ,  Lars Helge Thylen ,  Fung Suong Ou ,  Min Hu

    IPC分类号： G01J3/44

    CPC分类号： G01N21/658

    摘要： An apparatus for performing SERS includes a substrate and flexible nano-fingers, each of the nano-fingers having a first end attached to the substrate, a free second end, and a body portion extending between the first end and the second end, in which the nano-fingers are arranged in an array on the substrate. The apparatus also includes an active material layer disposed on each of the second ends of the plurality of nano-fingers, in which the nano-fingers are to be in a substantially collapsed state in which the active layers on at least two of the nano-fingers contact each other under dominant attractive forces between the plurality of nano-fingers and in which the active material layers are to repel each other when the active material layers are electrostatically charged.

    摘要翻译： 用于执行SERS的装置包括基底和柔性纳米指，每个纳米指具有连接到基底的第一端，自由的第二端和在第一端和第二端之间延伸的主体部分，其中 纳米手指以阵列排列在基板上。 该装置还包括设置在多个纳米手指的每个第二端上的活性材料层，其中纳米指状物将处于基本上塌陷的状态，其中在至少两个纳米手指上的活性层， 手指在多个纳米手指之间的主导吸引力下彼此接触，并且当活性材料层被静电充电时，活性材料层将彼此排斥。

    Luminescent chemical sensor integrated with at least one molecular trap
    2.
    发明授权
    Luminescent chemical sensor integrated with at least one molecular trap 有权
    与至少一个分子陷阱集成的发光化学传感器

    公开(公告)号：US08404491B2

    公开(公告)日：2013-03-26

    申请号：US12916299

    申请日：2010-10-29

    申请人： Zhiyong Li ,  Michael Josef Stuke ,  Shih-Yuan Wang ,  Huei Pei Kuo

    发明人： Zhiyong Li ,  Michael Josef Stuke ,  Shih-Yuan Wang ,  Huei Pei Kuo

    IPC分类号： G01N21/76

    CPC分类号： G01N33/5438 ,  B82Y15/00 ,  G01N21/648 ,  G01N21/658 ,  Y10T436/25

    摘要： A luminescent chemical sensor integrated with at least one molecular trap. The luminescent chemical sensor includes at least one molecular trap and at least one metallic-nanofinger device integrated with at least one molecular trap. The molecular trap includes a plurality of electrodes that trap at least one analyte molecule. The metallic-nanofinger device includes a substrate, and a plurality of nanofingers coupled with the substrate. A nanofinger of the plurality includes a flexible column, and a metallic cap coupled to an apex of the flexible column. At least the nanofinger and a second nanofinger of the plurality of nanofingers are to self-arrange into a close-packed configuration with the analyte molecule. A method for using, and a chemical-analysis apparatus including the luminescent chemical sensor are also provided.

    摘要翻译： 与至少一个分子阱集成的发光化学传感器。 发光化学传感器包括至少一个分子阱和至少一个与至少一个分子陷阱集成的金属纳米酮装置。 分子阱包括捕获至少一种分析物分子的多个电极。 金属纳米装置包括衬底和与衬底耦合的多个纳米器件。 多个纳米针板包括柔性柱和联接到柔性柱的顶点的金属帽。 至少纳米角蛋白和多个纳米针的第二纳米梳理器将自分配成与分析物分子紧密堆积的构型。 还提供了使用方法和包括发光化学传感器的化学分析装置。

    MOLECULE DETECTION USING RAMAN LIGHT DETECTION
    4.
    发明申请
    MOLECULE DETECTION USING RAMAN LIGHT DETECTION 失效
    使用拉曼光检测的分子检测

    公开(公告)号：US20110188033A1

    公开(公告)日：2011-08-04

    申请号：US12696853

    申请日：2010-01-29

    申请人： Min Hu ,  Alexandre M. Bratkovski ,  Jingjing Li ,  Huei Pei Kuo ,  Zhiyong Li ,  Fung Suong Ou ,  Michael Josef Stuke ,  Michael Renne Ty Tan ,  Shih-Yuan Wang ,  Wei Wu

    发明人： Min Hu ,  Alexandre M. Bratkovski ,  Jingjing Li ,  Huei Pei Kuo ,  Zhiyong Li ,  Fung Suong Ou ,  Michael Josef Stuke ,  Michael Renne Ty Tan ,  Shih-Yuan Wang ,  Wei Wu

    IPC分类号： G01J3/44

    CPC分类号： G01J3/44

    摘要： An apparatus for detecting at least one molecule using Raman light detection includes a substrate for supporting a sample containing the at least one molecule, a laser source for emitting a laser beam to cause Raman light emission from the at least one molecule, a modulating element for modulating a spatial relationship between the laser beam and the substrate at an identified frequency to cause the Raman light to be emitted from the at least one molecule at the identified frequency, at least one detector for detecting the Raman light emitted from the at least one molecule, and a post-signal processing unit configured to process the detected Raman light emission at the identified frequency to detect the at least one molecule.

    摘要翻译： 用于使用拉曼光检测检测至少一个分子的装置包括用于支撑含有至少一个分子的样品的基底，用于发射激光束以产生来自至少一个分子的拉曼光发射的激光源， 以识别的频率调制激光束和衬底之间的空间关系，以使所述拉曼光以所识别的频率从所述至少一个分子发射;至少一个检测器，用于检测从所述至少一个分子发射的拉曼光 以及后信号处理单元，被配置为处理所识别的频率处的所检测的拉曼光发射以检测所述至少一个分子。

    LUMINESCENT CHEMICAL SENSOR INTEGRATED WITH AT LEAST ONE MOLECULAR TRAP
    7.
    发明申请
    LUMINESCENT CHEMICAL SENSOR INTEGRATED WITH AT LEAST ONE MOLECULAR TRAP 有权
    LUMINESCENT化学传感器与最少的一个分子轨迹集成

    公开(公告)号：US20120107948A1

    公开(公告)日：2012-05-03

    申请号：US12916299

    申请日：2010-10-29

    申请人： Zhiyong LI ,  Michael Josef Stuke ,  Shih-Yuan Wang ,  Huei Pei Kuo

    发明人： Zhiyong LI ,  Michael Josef Stuke ,  Shih-Yuan Wang ,  Huei Pei Kuo

    IPC分类号： G01N21/75 ,  G01N33/48 ,  C40B60/00 ,  G01N1/00

    CPC分类号： G01N33/5438 ,  B82Y15/00 ,  G01N21/648 ,  G01N21/658 ,  Y10T436/25

    摘要： A luminescent chemical sensor integrated with at least one molecular trap. The luminescent chemical sensor includes at least one molecular trap and at least one metallic-nanofinger device integrated with at least one molecular trap. The molecular trap includes a plurality of electrodes that trap at least one analyte molecule. The metallic-nanofinger device includes a substrate, and a plurality of nanofingers coupled with the substrate. A nanofinger of the plurality includes a flexible column, and a metallic cap coupled to an apex of the flexible column. At least the nanofinger and a second nanofinger of the plurality of nanofingers are to self-arrange into a close-packed configuration with the analyte molecule. A method for using, and a chemical-analysis apparatus including the luminescent chemical sensor are also provided.

    摘要翻译： 与至少一个分子阱集成的发光化学传感器。 发光化学传感器包括至少一个分子阱和至少一个与至少一个分子陷阱集成的金属纳米酮装置。 分子阱包括捕获至少一种分析物分子的多个电极。 金属纳米装置包括衬底和与衬底耦合的多个纳米器件。 多个纳米针板包括柔性柱和联接到柔性柱的顶点的金属帽。 至少纳米角蛋白和多个纳米针的第二纳米梳理器将自分配成与分析物分子紧密堆积的构型。 还提供了使用方法和包括发光化学传感器的化学分析装置。

    Apparatus for performing SERS
    8.
    发明授权
    Apparatus for performing SERS 有权
    用于执行SERS的装置

    公开(公告)号：US08665432B2

    公开(公告)日：2014-03-04

    申请号：US12915148

    申请日：2010-10-29

    申请人： Min Hu ,  Michael Josef Stuke ,  Zhiyong Li ,  Wei Wu ,  Fung Suong Ou ,  Shih-Yuan Wang ,  Lars Helge Thylen

    发明人： Min Hu ,  Michael Josef Stuke ,  Zhiyong Li ,  Wei Wu ,  Fung Suong Ou ,  Shih-Yuan Wang ,  Lars Helge Thylen

    IPC分类号： G01N21/65

    CPC分类号： G01J3/44 ,  G01N21/658

    摘要： An apparatus for performing surface enhanced Raman spectroscopy (SERS) includes a substrate and a plurality of nano-pillars, each of the plurality of nano-pillars having a first end attached to the substrate, a second end located distally from the substrate, and a body portion extending between the first end and the second end, in which the plurality of nano-pillars are arranged in an array on the substrate, and in which each of the plurality of nano-pillars is formed of a polymer material that is functionalized to expand in the presence of a fluid to cause gaps between the plurality of nano-pillars to shrink when the fluid is supplied onto the nano-pillars.

    摘要翻译： 用于进行表面增强拉曼光谱（SERS）的设备包括基底和多个纳米柱，多个纳米柱中的每一个具有连接到基底的第一端，位于远离基底的第二端，以及 主体部分在所述第一端和所述第二端之间延伸，其中所述多个纳米柱以阵列布置在所述基底上，并且所述多个纳米柱中的每一个由聚合物材料形成，所述聚合物材料被官能化为 在存在流体的情况下膨胀，以便当将流体供应到纳米支柱上时，使多个纳米柱之间的间隙收缩。

    Molecule detection using Raman light detection
    9.
    发明授权
    Molecule detection using Raman light detection 失效
    使用拉曼光检测的分子检测

    公开(公告)号：US08208137B2

    公开(公告)日：2012-06-26

    申请号：US12696853

    申请日：2010-01-29

    申请人： Min Hu ,  Alexandre M. Bratkovski ,  Jingjing Li ,  Huei Pei Kuo ,  Zhiyong Li ,  Fung Suong Ou ,  Michael Josef Stuke ,  Michael Renne Ty Tan ,  Shih-Yuan Wang ,  Wei Wu

    发明人： Min Hu ,  Alexandre M. Bratkovski ,  Jingjing Li ,  Huei Pei Kuo ,  Zhiyong Li ,  Fung Suong Ou ,  Michael Josef Stuke ,  Michael Renne Ty Tan ,  Shih-Yuan Wang ,  Wei Wu

    IPC分类号： G01J3/44

    CPC分类号： G01J3/44

    摘要： An apparatus for detecting at least one molecule using Raman light detection includes a substrate for supporting a sample containing the at least one molecule, a laser source for emitting a laser beam to cause Raman light emission from the at least one molecule, a modulating element for modulating a spatial relationship between the laser beam and the substrate at an identified frequency to cause the Raman light to be emitted from the at least one molecule at the identified frequency, at least one detector for detecting the Raman light emitted from the at least one molecule, and a post-signal processing unit configured to process the detected Raman light emission at the identified frequency to detect the at least one molecule.

    摘要翻译： 用于使用拉曼光检测检测至少一个分子的装置包括用于支撑含有至少一个分子的样品的基底，用于发射激光束以产生来自至少一个分子的拉曼光发射的激光源， 以识别的频率调制激光束和衬底之间的空间关系，以使所述拉曼光以所识别的频率从所述至少一个分子发射;至少一个检测器，用于检测从所述至少一个分子发射的拉曼光 以及后信号处理单元，被配置为处理所识别的频率处的所检测的拉曼光发射以检测所述至少一个分子。

    APPARATUS FOR PERFORMING SERS
    10.
    发明申请
    APPARATUS FOR PERFORMING SERS 有权
    执行人员的设备

    公开(公告)号：US20120105841A1

    公开(公告)日：2012-05-03

    申请号：US12915148

    申请日：2010-10-29

    申请人： Min Hu ,  Michael Josef Stuke ,  Zhiyong Li ,  Wei Wu ,  Fung Suong Ou ,  Shih-Yuan Wang ,  Lars Helge Thylen

    发明人： Min Hu ,  Michael Josef Stuke ,  Zhiyong Li ,  Wei Wu ,  Fung Suong Ou ,  Shih-Yuan Wang ,  Lars Helge Thylen

    IPC分类号： G01J3/44

    CPC分类号： G01J3/44 ,  G01N21/658

    摘要： An apparatus for performing surface enhanced Raman spectroscopy (SERS) includes a substrate and a plurality of nano-pillars, each of the plurality of nano-pillars having a first end attached to the substrate, a second end located distally from the substrate, and a body portion extending between the first end and the second end, in which the plurality of nano-pillars are arranged in an array on the substrate, and in which each of the plurality of nano-pillars is formed of a polymer material that is functionalized to expand in the presence of a fluid to cause gaps between the plurality of nano-pillars to shrink when the fluid is supplied onto the nano-pillars.

    摘要翻译： 用于进行表面增强拉曼光谱（SERS）的设备包括基底和多个纳米柱，多个纳米柱中的每一个具有连接到基底的第一端，位于远离基底的第二端，以及 主体部分在所述第一端和所述第二端之间延伸，其中所述多个纳米柱以阵列布置在所述基底上，并且所述多个纳米柱中的每一个由聚合物材料形成，所述聚合物材料被官能化为 在存在流体的情况下膨胀，以便当将流体供应到纳米支柱上时，使多个纳米柱之间的间隙收缩。