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    Method for quantifying solutions comprised of multiple analytes
    1.
    发明授权
    Method for quantifying solutions comprised of multiple analytes 有权

    公开(公告)号：US12092521B2

    公开(公告)日：2024-09-17

    申请号：US17685595

    申请日：2022-03-03

    Applicant: Finesse Solutions, Inc.

    Inventor： Mark Selker ,  Barbara Paldus

    IPC: G01J3/44 ,  G01J3/02 ,  G01N21/65 ,  G02B6/02

    CPC classification number: G01J3/44 ,  G01J3/0218 ,  G01N21/65 ,  G02B6/02385 ,  G01N2201/08 ,  G01N2201/129 ,  G02B6/02328

    Abstract: A method of determining the identity and concentration of a target analyte present in a biological sample includes: introducing a first target analyte into a hollow core of an optical fiber; introducing a first reference calibrant into the hollow core of the optical fiber; transmitting light from a laser light source through the hollow core of the optical fiber and the first target analyte to generate a first Raman anti-Stokes analyte emission corresponding to the first target analyte; receiving the first Raman anti-Stokes analyte emission at a spectral analysis system optically coupled to the optical fiber; and deriving Raman anti-Stokes spectral peaks or spectra of the first target analyte at the spectral analysis system based on the first Raman anti-Stokes analyte emission.

    Double-walled containment cell
    4.
    发明授权
    Double-walled containment cell 有权

    公开(公告)号：US11927525B2

    公开(公告)日：2024-03-12

    申请号：US17523333

    申请日：2021-11-10

    Applicant: BATTELLE SAVANNAH RIVER ALLIANCE, LLC

    Inventor： Eliel Villa-Aleman ,  Michael C. Maxwell ,  Don D. Dick, Jr.

    IPC: G01N21/03 ,  G01J3/44 ,  G01N21/01

    CPC classification number: G01N21/01 ,  G01J3/44 ,  G01N21/03

    Abstract: Double-walled containment cells are described as may be used for storage, transport, and examination of a sample held within the cell by use of optical analysis techniques. A double-walled containment cell can include multiple types of windows that can be located as desired on the containment cells and thereby provide for optical access to a sample for multiple optical analysis techniques. Disclosed containment cells can be sized and designed for use with existing optical analysis systems, e.g., laser ablation, X-ray diffraction, spectral analysis (e.g., Raman spectroscopy, infrared spectroscopy, laser-induced breakdown spectroscopy, etc.), imaging analysis, etc.

    Fiber optic probe having components and features that improve performance
    5.
    发明授权
    Fiber optic probe having components and features that improve performance 有权

    公开(公告)号：US11867948B2

    公开(公告)日：2024-01-09

    申请号：US17375688

    申请日：2021-07-14

    Applicant: Eric Todd Marple ,  Kirk David Urmey ,  John Meckert

    Inventor： Eric Todd Marple ,  Kirk David Urmey ,  John Meckert

    IPC: G01J3/44 ,  G02B6/36 ,  G02B6/293

    CPC classification number: G02B6/29368 ,  G01J3/44 ,  G02B6/3624

    Abstract: A fiber optic probe is provided with a distal sampling end, a proximal end, and light delivery and collection paths therethrough. The probe includes a window disposed at the distal sampling end of the fiber optic probe, the window having a distal end and a proximal end. A lens is disposed at the proximal end of the window, the lens having a distal end, a proximal end, and an aperture. A light delivery optical fiber is provided having a distal end and a proximal end, the distal end being received by the lens aperture. An optical isolator provided within the lens aperture to optically isolate the light delivery path and the light collection path. A collection optical fiber is provided in optical communication with the fiber collection filter. The probe may include a lens collection filter disposed between the window and the lens.

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