公开(公告)号：US20110046104A1

公开(公告)日：2011-02-24

申请号：US12598277

申请日：2009-10-30

申请人： Michael Paul Mortimore ,  Julian M.C. Golec ,  Daniel David Robinson ,  John Studley

发明人： Michael Paul Mortimore ,  Julian M.C. Golec ,  Daniel David Robinson ,  John Studley

IPC分类号： A61K31/506 ,  C07D417/14 ,  C07D403/14 ,  C07D401/14

CPC分类号： C07D403/12 ,  C07D417/14

摘要： The present invention relates to compounds useful as inhibitors of Aurora protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention.

公开(公告)号：US20110060013A1

公开(公告)日：2011-03-10

申请号：US12601026

申请日：2009-11-20

申请人： Michael Paul Mortimore ,  Christopher John Davis ,  Julian M.C. Golec ,  John Studley ,  Daniel David Robinson

发明人： Michael Paul Mortimore ,  Christopher John Davis ,  Julian M.C. Golec ,  John Studley ,  Daniel David Robinson

IPC分类号： A61K31/4439 ,  C07D401/14 ,  C07D417/14 ,  A61P35/00

CPC分类号： C07D401/14 ,  C07D417/14

摘要： The present invention relates to compounds useful as inhibitors of Aurora protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention.

摘要翻译： 本发明涉及可用作Aurora蛋白激酶抑制剂的化合物。 本发明还提供包含这些化合物的药学上可接受的组合物和使用该化合物和组合物治疗各种疾病，病症和障碍的方法。 本发明还提供了制备本发明化合物的方法。

公开(公告)号：US20100215772A1

公开(公告)日：2010-08-26

申请号：US12598276

申请日：2009-10-30

申请人： Michael Mortimore ,  Julian M.C. Golec ,  Daniel David Robinson ,  John Studley

发明人： Michael Mortimore ,  Julian M.C. Golec ,  Daniel David Robinson ,  John Studley

IPC分类号： A61K33/24 ,  C07D239/46 ,  A61K31/495 ,  A61K31/506 ,  A61K31/517 ,  A61K31/5377 ,  A61K31/513 ,  A61P35/00

CPC分类号： C07D403/12 ,  C07D417/14

摘要： The present invention relates to compounds useful as inhibitors of Aurora protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention.

摘要翻译： 本发明涉及可用作Aurora蛋白激酶抑制剂的化合物。 本发明还提供包含这些化合物的药学上可接受的组合物和使用该化合物和组合物治疗各种疾病，病症和障碍的方法。 本发明还提供了制备本发明化合物的方法。