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公开(公告)号:US07033574B1
公开(公告)日:2006-04-25
申请号:US08893371
申请日:1997-07-15
申请人: Michel Schneider , Daniel Bichon , Philippe Bussat , Jerone Puginier , Eva Hybl
发明人: Michel Schneider , Daniel Bichon , Philippe Bussat , Jerone Puginier , Eva Hybl
IPC分类号: A61B8/00
CPC分类号: A61K49/223 , A61K49/227 , Y10S514/975
摘要: Gas or air filled microbubble suspensions in aqueous phases usable as imaging contrast agents in ultrasonic echography. They contain laminarized surfactants and, optionally, hydrophilic stabilizers. The laminarized surfactants can be in the form of liposomes. The suspensions are obtained by exposing the laminarized surfactants to air or a gas before or after admixing with an aqueous phase.
摘要翻译: 在超声波回波成像中用作成像造影剂的水相中的气体或空气填充的微泡悬浮液。 它们含有层状表面活性剂和任选的亲水稳定剂。 层状表面活性剂可以是脂质体的形式。 通过在与水相混合之前或之后将层状表面活性剂暴露于空气或气体中获得悬浮液。