公开(公告)号：US20090215755A1

公开(公告)日：2009-08-27

申请号：US12463652

申请日：2009-05-11

申请人： Michele Arnone ,  Jean Marc Herbert ,  Hassan Massoud Heshmati ,  Philip Janiak ,  Mohammed Bensaid

发明人： Michele Arnone ,  Jean Marc Herbert ,  Hassan Massoud Heshmati ,  Philip Janiak ,  Mohammed Bensaid

IPC分类号： A61K31/454 ,  A61P3/04 ,  A61P3/10 ,  A61P9/00 ,  A61K31/549

CPC分类号： A61K31/4178 ,  A61K31/366 ,  A61K31/454 ,  A61K31/5415 ,  A61K2300/00

摘要： Use of a pyrazole-derived compound that is an antagonist for cannabinoid CB1 receptors, alone or combined with another active principal, for preparing medicinal products that are useful in the prevention and treatment of dyslipidemias and of diseases related to dyslipidemias and/or to obesity, such as metabolic syndrome, cardiovascular risks and hepatic diseases.

摘要翻译： 作为大麻素CB1受体的拮抗剂的单独或与另一活性成分组合的吡唑衍生化合物用于制备可用于预防和治疗血脂异常和与血脂异常和/或肥胖有关的疾病的药物的用途， 如代谢综合征，心血管风险和肝脏疾病。