公开(公告)号：US20210347888A1

公开(公告)日：2021-11-11

申请号：US17239010

申请日：2021-04-23

申请人： Millennium Pharmaceuticals, Inc.

发明人： Daniel Tavares ,  Bianka Prinz ,  James Geoghegan

IPC分类号： C07K16/28

摘要： Antibodies, fragments thereof and fusion proteins that specifically bind to CD19, are described, as well as methods of making and using such antibodies. Such antibodies, fusion proteins and fragments thereof are useful for the treatment and diagnosis of various B-cell disorders, including B-cell malignancies and autoimmune diseases.

公开(公告)号：US12049499B2

公开(公告)日：2024-07-30

申请号：US17239010

申请日：2021-04-23

申请人： Millennium Pharmaceuticals, Inc.

发明人： Daniel Tavares ,  Bianka Prinz ,  James Geoghegan

IPC分类号： C07K16/28

CPC分类号： C07K16/2803 ,  C07K2317/565 ,  C07K2317/622 ,  C07K2317/732 ,  C07K2317/92

摘要： Antibodies, fragments thereof and fusion proteins that specifically bind to CD19, are described, as well as methods of making and using such antibodies. Such antibodies, fusion proteins and fragments thereof are useful for the treatment and diagnosis of various B-cell disorders, including B-cell malignancies and autoimmune diseases.