公开(公告)号：US20230285386A1

公开(公告)日：2023-09-14

申请号：US18199244

申请日：2023-05-18

申请人： Mind Medicine, Inc.

发明人： Peter MACK ,  Dustin MELTON ,  Bethany Amber DOTY ,  Jon SCHROEDER ,  James COGHILL ,  Daniel Emil LEVY

IPC分类号： A61K31/48 ,  A61K9/20 ,  A61K47/60 ,  A61K47/22 ,  A61K47/36 ,  A61K47/69 ,  A61K47/26 ,  A61K47/10 ,  A61K9/00

CPC分类号： A61K31/48 ,  A61K9/0056 ,  A61K9/20 ,  A61K9/2013 ,  A61K9/2054 ,  A61K9/2095 ,  A61K47/10 ,  A61K47/22 ,  A61K47/26 ,  A61K47/36 ,  A61K47/60 ,  A61K47/6923

摘要： A solid oral immediate release formulation of LSD, including LSD contained within a dosage form of a capsule, tablet, or orally disintegrating tablet. A method of making a solid oral immediate release formulation of LSD as a free base or in a salt form by granulation, including moisture-activated dry granulation or dry blending. A method of treating an individual, by administering a solid oral immediate release formulation of LSD and treating the individual.

公开(公告)号：US20220370413A1

公开(公告)日：2022-11-24

申请号：US17883509

申请日：2022-08-08

申请人： Mind Medicine, Inc.

发明人： Robert BARROW ,  Peter MACK ,  Stephen SCHNEIDER ,  Jon SCHROEDER ,  Gerald S. JONES, JR.

IPC分类号： A61K31/4045

摘要： A composition of psilocin that is stable including at least one agent or chemical modification that provides enhanced stability. A method making stable psilocin, by providing a formulation of psilocin including at least one agent or chemical modification that provides enhanced stability. A method of treatment of a disease or condition, by administering a composition of psilocin that is stable to an individual and treating the disease or condition.

公开(公告)号：US20230075847A1

公开(公告)日：2023-03-09

申请号：US17890133

申请日：2022-08-17

申请人： Mind Medicine, Inc.

发明人： Peter MACK ,  Timm TRENKTROG ,  Dustin MELTON ,  Bethany Amber DOTY ,  Jon SCHROEDER ,  Lisa Marie GARRETT

IPC分类号： A61K9/20 ,  A61K9/00 ,  A61K31/48

摘要： A solid oral immediate release formulation of LSD, wherein the composition is produced by lyophilization of a feedstock in a pre-formed mold to form an orally disintegrating tablet. A method of making a solid oral immediate release formulation of LSD by lyophilizing a flash frozen stock solution of LSD and excipients, including a non-gelling matrix former, filler, and binder in a pre-formed mold, and forming an orally disintegrating tablet. A method of treating an individual by administering a solid oral immediate release formulation of LSD, wherein the composition is produced by lyophilization of a feedstock in a pre-formed mold to form an orally disintegrating tablet and treating the individual.

公开(公告)号：US20230285359A1

公开(公告)日：2023-09-14

申请号：US18326480

申请日：2023-05-31

申请人： Mind Medicine, Inc.

发明人： Robert BARROW ,  Peter MACK ,  Stephen SCHNEIDER ,  Jon SCHROEDER ,  Gerald S. JONES

IPC分类号： A61K31/4045

CPC分类号： A61K31/4045

摘要： A composition of psilocin that is stable including at least one agent or chemical modification that provides enhanced stability. A method making stable psilocin, by providing a formulation of psilocin including at least one agent or chemical modification that provides enhanced stability. A method of treatment of a disease or condition, by administering a composition of psilocin that is stable to an individual and treating the disease or condition.

公开(公告)号：US20230122949A1

公开(公告)日：2023-04-20

申请号：US18077085

申请日：2022-12-07

申请人： Mind Medicine, Inc.

发明人： Peter MACK ,  Timm TRENKTROG ,  Dustin MELTON ,  Bethany Amber DOTY ,  Jon SCHROEDER ,  Lisa Marie GARRETT

IPC分类号： A61K9/20 ,  A61K31/48 ,  A61K9/00

摘要： A solid oral immediate release formulation of LSD, wherein the composition is produced by lyophilization of a feedstock in a pre-formed mold to form an orally disintegrating tablet. A method of making a solid oral immediate release formulation of LSD by lyophilizing a flash frozen stock solution of LSD and excipients, including a non-gelling matrix former, filler, and binder in a pre-formed mold, and forming an orally disintegrating tablet. A method of treating an individual by administering a solid oral immediate release formulation of LSD, wherein the composition is produced by lyophilization of a feedstock in a pre-formed mold to form an orally disintegrating tablet and treating the individual.

公开(公告)号：US20220280482A1

公开(公告)日：2022-09-08

申请号：US17687568

申请日：2022-03-04

申请人： Mind Medicine, Inc.

发明人： Robert BARROW ,  Peter MACK ,  Stephen SCHNEIDER ,  Jon SCHROEDER

IPC分类号： A61K31/4045

摘要： A composition of psilocin that is stable including at least one agent or chemical modification that provides enhanced stability. A method making stable psilocin, by providing a formulation of psilocin including at least one agent or chemical modification that provides enhanced stability. A method of treatment of a disease or condition, by administering a composition of psilocin that is stable to an individual, and treating the disease or condition.

公开(公告)号：US20230218532A1

公开(公告)日：2023-07-13

申请号：US18194761

申请日：2023-04-03

申请人： Mind Medicine, Inc.

发明人： Peter MACK ,  Timm TRENKTROG ,  Dustin MELTON ,  Bethany Amber DOTY ,  Jon SCHROEDER ,  Lisa Marie GARRETT

IPC分类号： A61K31/48 ,  A61K9/20

CPC分类号： A61K31/48 ,  A61K9/205 ,  A61K9/2054 ,  A61K9/2018 ,  A61K9/2095

摘要： A solid oral immediate release formulation of LSD, wherein the composition is produced by lyophilization of a feedstock in a pre-formed mold to form an orally disintegrating tablet. A method of making a solid oral immediate release formulation of LSD by lyophilizing a flash frozen stock solution of LSD and excipients, including a non-gelling matrix former, filler, and binder in a pre-formed mold, and forming an orally disintegrating tablet. A method of treating an individual by administering a solid oral immediate release formulation of LSD, wherein the composition is produced by lyophilization of a feedstock in a pre-formed mold to form an orally disintegrating tablet and treating the individual.

公开(公告)号：US20230064429A1

公开(公告)日：2023-03-02

申请号：US17890198

申请日：2022-08-17

申请人： Mind Medicine, Inc.

发明人： Peter MACK ,  Dustin MELTON ,  Bethany Amber DOTY ,  Jon SCHROEDER ,  James COGHILL

IPC分类号： A61K31/48 ,  A61K9/20 ,  A61K47/60 ,  A61K47/10 ,  A61K47/36 ,  A61K47/69 ,  A61K47/26 ,  A61K47/22

摘要： A solid oral immediate release formulation of LSD, including LSD contained within a dosage form of a capsule, tablet, or orally disintegrating tablet. A method of making a solid oral immediate release formulation of LSD as a free base or in a salt form by granulation, including moisture-activated dry granulation or dry blending. A method of treating an individual, by administering a solid oral immediate release formulation of LSD and treating the individual.