公开(公告)号：US10927374B2

公开(公告)日：2021-02-23

申请号：US16125048

申请日：2018-09-07

Applicant: Monsanto Technology LLC ,  Beeologics, Inc. ,  The United States of America, as represented by the Secretary of Agriculture

Inventor： Alex Inberg ,  Mahak Kapoor ,  Jay Evans

IPC: C12N15/113 ,  A61K31/713 ,  A01K51/00 ,  A01N37/46 ,  A01N63/10

Abstract: This application provides and discloses anti-parasitic, anti-pest or insecticidal nucleic acid molecules and their calmodulin target genes for the control of arthropod parasites and pests. This application further provides methods and compositions for the control and treatment of parasites and pests in Apis mellifera (honey bee) hives.

公开(公告)号：US20180066278A1

公开(公告)日：2018-03-08

申请号：US15819840

申请日：2017-11-21

Applicant: Monsanto Technology LLC

Inventor： Jodi Lynn BEATTIE ,  Michael John Crawford ,  Brian Donovan Eads ,  Lex Evan Flagel ,  Mahak Kapoor ,  Christina Marie Taylor

IPC: C12N15/82 ,  A01N57/16 ,  C12N15/113 ,  C07K14/435

Abstract: Disclosed herein are methods of controlling insect pests, in particular Leptinotarsa spp. which infest crop plants, and methods of providing plants resistant to such pests. Also disclosed are polynucleotides and recombinant DNA molecules and constructs useful in such methods, insecticidal compositions such as topical sprays containing insecticidal double-stranded RNAs, and solanaceous plants with improved resistance to infestation by Leptinotarsa spp. Further disclosed are methods of selecting target genes for RNAi-mediated silencing and control of Leptinotarsa spp.

公开(公告)号：US20150240258A1

公开(公告)日：2015-08-27

申请号：US14603347

申请日：2015-01-22

Applicant: MONSANTO TECHNOLOGY LLC

Inventor： Jodi Lynn Beattie ,  Michael John Crawford ,  Brian Donovan Eads ,  Lex Evan Flagel ,  Mahak Kapoor ,  Christina Marie Taylor

IPC: C12N15/82 ,  A01N57/16 ,  C12N15/113

CPC classification number: C12N15/8286 ,  A01N57/16 ,  A01N63/02 ,  C07K14/43563 ,  C12N15/113 ,  C12N15/8218 ,  C12N2310/14 ,  Y02A40/162

Abstract: Disclosed herein are methods of controlling insect pests, in particular Leptinotarsa spp. which infest crop plants, and methods of providing plants resistant to such pests. Also disclosed are polynucleotides and recombinant DNA molecules and constructs useful in such methods, insecticidal compositions such as topical sprays containing insecticidal double-stranded RNAs, and solanaceous plants with improved resistance to infestation by Leptinotarsa spp. Further disclosed are methods of selecting target genes for RNAi-mediated silencing and control of Leptinotarsa spp.

公开(公告)号：US20150143580A1

公开(公告)日：2015-05-21

申请号：US14335135

申请日：2014-07-18

Applicant: MONSANTO TECHNOLOGY LLC

Inventor： Jodi Lynn Beattie ,  Michael John Crawford ,  Brian Donovan Eads ,  Lex Evan Flagel ,  Mahak Kapoor ,  Christina Marie Taylor

IPC: C12N15/82 ,  A01N57/16 ,  C12N15/113

CPC classification number: C12N15/8286 ,  A01N57/16 ,  C07K14/43563 ,  C12N15/113 ,  C12N15/8218 ,  C12N2310/14 ,  Y02A40/162

Abstract: Disclosed herein are methods of controlling insect pests, in particular Leptinotarsa spp. which infest crop plants, and methods of providing plants resistant to such pests. Also disclosed are polynucleotides and recombinant DNA molecules and constructs useful in such methods, insecticidal compositions such as topical sprays containing insecticidal double-stranded RNAs, and solanaceous plants with improved resistance to infestation by Leptinotarsa spp. Further disclosed are methods of selecting target genes for RNAi-mediated silencing and control of Leptinotarsa spp.

Abstract translation: 本文公开了防治害虫，特别是Leptinotarsa spp的方法。 侵染作物的植物，以及提供对这些害虫有抗性的植物的方法。 还公开了可用于这些方法的多核苷酸和重组DNA分子和构建体，杀虫组合物，例如含有杀虫双链RNA的局部喷雾剂，以及具有改良的抗Leptinotarsa spp侵染的茄科植物。 进一步公开了选择RNAi介导的沉默和控制Leptinotarsa spp的靶基因的方法。

公开(公告)号：US10597676B2

公开(公告)日：2020-03-24

申请号：US15819840

申请日：2017-11-21

Applicant: Monsanto Technology LLC

Inventor： Jodi Lynn Beattie ,  Michael John Crawford ,  Brian Donovan Eads ,  Lex Evan Flagel ,  Mahak Kapoor ,  Christina Marie Taylor

IPC: C12N15/82 ,  C12N15/11 ,  C12N15/113

Abstract: Disclosed herein are methods of controlling insect pests, in particular Leptinotarsa spp. which infest crop plants, and methods of providing plants resistant to such pests. Also disclosed are polynucleotides and recombinant DNA molecules and constructs useful in such methods, insecticidal compositions such as topical sprays containing insecticidal double-stranded RNAs, and solanaceous plants with improved resistance to infestation by Leptinotarsa spp. Further disclosed are methods of selecting target genes for RNAi-mediated silencing and control of Leptinotarsa spp.

公开(公告)号：US09850496B2

公开(公告)日：2017-12-26

申请号：US14603347

申请日：2015-01-22

Applicant: Monsanto Technology LLC

Inventor： Jodi Lynn Beattie ,  Michael John Crawford ,  Brian Donovan Eads ,  Lex Evan Flagel ,  Mahak Kapoor ,  Christina Marie Taylor

IPC: C12N15/82 ,  C12N15/113 ,  A01N57/16 ,  C07K14/435 ,  A01N63/02

CPC classification number: C12N15/8286 ,  A01N57/16 ,  A01N63/02 ,  C07K14/43563 ,  C12N15/113 ,  C12N15/8218 ,  C12N2310/14 ,  Y02A40/162

Abstract: Disclosed herein are methods of controlling insect pests, in particular Leptinotarsa spp. which infest crop plants, and methods of providing plants resistant to such pests. Also disclosed are polynucleotides and recombinant DNA molecules and constructs useful in such methods, insecticidal compositions such as topical sprays containing insecticidal double-stranded RNAs, and solanaceous plants with improved resistance to infestation by Leptinotarsa spp. Further disclosed are methods of selecting target genes for RNAi-mediated silencing and control of Leptinotarsa spp.

公开(公告)号：US20150203867A1

公开(公告)日：2015-07-23

申请号：US14608951

申请日：2015-01-29

Applicant: MONSANTO TECHNOLOGY LLC

Inventor： Jodi Lynn Beattie ,  Michael John Crawford ,  Brian Donovan Eads ,  Lex Evan Flagel ,  Mahak Kapoor ,  Christina Marie Taylor

IPC: C12N15/82 ,  C12N15/113

CPC classification number: C12N15/8286 ,  A01N57/16 ,  C07K14/43563 ,  C12N15/113 ,  C12N15/8218 ,  C12N2310/14 ,  Y02A40/162

Abstract: Disclosed herein are methods of controlling insect pests, in particular Leptinotarsa spp. which infest crop plants, and methods of providing plants resistant to such pests. Also disclosed are polynucleotides and recombinant DNA molecules and constructs useful in such methods, insecticidal compositions such as topical sprays containing insecticidal double-stranded RNAs, and solanaceous plants with improved resistance to infestation by Leptinotarsa spp. Further disclosed are methods of selecting target genes for RNAi-mediated silencing and control of Leptinotarsa spp.

公开(公告)号：US20150159156A1

公开(公告)日：2015-06-11

申请号：US14532596

申请日：2014-11-04

Applicant: Monsanto Technology LLC ,  Beeologics Inc. ,  The United States of America, as represented by the Secretary of Agriculture

Inventor： Alex Inberg ,  Mahak Kapoor ,  Jay Evans

IPC: C12N15/113 ,  A61K31/713 ,  A01K51/00

CPC classification number: C12N15/113 ,  A01K51/00 ,  A01N37/46 ,  A01N63/02 ,  A61K31/713 ,  C12N2310/14 ,  C12N2310/531

Abstract: This application provides and discloses anti-parasitic, anti-pest or insecticidal nucleic acid molecules and their calmodulin target genes for the control of arthropod parasites and pests. This application further provides methods and compositions for the control and treatment of parasites and pests in Apis mellifera (honey bee) hives.

Abstract translation: 本申请提供并公开了用于控制节肢动物寄生虫和害虫的抗寄生虫，抗病虫害或杀虫剂核酸分子及其钙调蛋白靶基因。 本申请还提供了用于控制和处理Apis mellifera（蜂蜜蜂）蜂巢中的寄生虫和害虫的方法和组合物。

公开(公告)号：US10968449B2

公开(公告)日：2021-04-06

申请号：US15545608

申请日：2016-01-21

Applicant: MONSANTO TECHNOLOGY LLC

Inventor： Jodi Lynn Beattie ,  Michael John Crawford ,  Brian Donovan Eads ,  Lex Evan Flagel ,  Mahak Kapoor ,  Christina Marie Taylor

IPC: C12N15/82 ,  C12N15/113 ,  C07K14/435 ,  A01N57/16

Abstract: Disclosed herein are methods of controlling insect pests, in particular Leptinotarsa spp. which infest crop plants, and methods of providing plants resistant to such pests. Also disclosed are polynucleotides and recombinant DNA molecules and constructs useful in such methods, insecticidal compositions such as topical sprays containing insecticidal double-stranded RNAs, and solanaceous plants with improved resistance to infestation by Leptinotarsa spp. Further disclosed are methods of selecting target genes for RNAi-mediated silencing and control of Leptinotarsa spp.

公开(公告)号：US20180371459A1

公开(公告)日：2018-12-27

申请号：US16125048

申请日：2018-09-07

Applicant: Monsanto Technology LLC ,  Beeologics, Inc. ,  The United States of America, as represented by the Secretary of Agriculture

Inventor： Alex Inberg ,  Mahak Kapoor ,  Jay Evans

IPC: C12N15/113 ,  A61K31/713 ,  A01N63/02 ,  A01K51/00 ,  A01N37/46

Abstract: This application provides and discloses anti-parasitic, anti-pest or insecticidal nucleic acid molecules and their calmodulin target genes for the control of arthropod parasites and pests. This application further provides methods and compositions for the control and treatment of parasites and pests in Apis mellifera (honey bee) hives.