专利检索 ap:("Monte Rosa Therapeutics, Inc.") AND inv:"Oliv Eidam" 第 1 页

1.

发明公开
COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF 审中-公开

公开(公告)号：US20240294495A1

公开(公告)日：2024-09-05

申请号：US18640909

申请日：2024-04-19

申请人： Monte Rosa Therapeutics, Inc.

发明人： Bernhard Fasching , Thomas Ryckmans , Alexander Flohr , Oliv Eidam , Andreas Ritzén

IPC分类号： C07D401/10 , A61K31/4523 , A61K31/4525 , A61K31/4545 , A61K31/5377 , C07D401/14 , C07D405/14

CPC分类号： C07D401/10 , A61K31/4523 , A61K31/4525 , A61K31/4545 , A61K31/5377 , C07D401/14 , C07D405/14

摘要： Described herein, in part, are compounds that bind to and modulate the surface of cereblon and mediate the degradation of GSPT1, and are therefore useful in the treatment of various disorders, such as cancer.

2.

发明公开
COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND USES THEREOF 审中-公开

公开(公告)号：US20240308976A1

公开(公告)日：2024-09-19

申请号：US18640889

申请日：2024-04-19

申请人： Monte Rosa Therapeutics, Inc.

发明人： Bernhard Fasching , Thomas Ryckmans , Oliv Eidam , Alexander Flohr , Laura Ann McAllister , Andreas Ritzén

IPC分类号： C07D401/10 , A61K31/4523 , A61K31/4525 , A61K31/453 , A61K31/4535 , A61K31/454 , A61K31/4545 , A61K31/506 , A61K31/5377 , A61K31/5386 , C07D401/14 , C07D405/14 , C07D409/14 , C07D491/107 , C07D498/08

CPC分类号： C07D401/10 , A61K31/4523 , A61K31/4525 , A61K31/453 , A61K31/4535 , A61K31/454 , A61K31/4545 , A61K31/506 , A61K31/5377 , A61K31/5386 , C07D401/14 , C07D405/14 , C07D409/14 , C07D491/107 , C07D498/08

摘要： Described herein, in part, are compounds that bind to and modulate the surface of cereblon and mediate the degradation of GSPT1, and are therefore useful in the treatment of various disorders, such as cancer.