公开(公告)号：US12006357B2

公开(公告)日：2024-06-11

申请号：US17255796

申请日：2019-06-26

Applicant: Mor Research Applications Ltd.

Inventor： Michael Fassler ,  Jacob George

IPC: C07K16/18 ,  A61K49/00 ,  A61P9/00 ,  G01N33/68

CPC classification number: C07K16/18 ,  A61K49/0008 ,  A61P9/00 ,  G01N33/6893 ,  C07K2317/14 ,  C07K2317/76

Abstract: The present disclosure provides antibodies and antigen-binding fragments thereof that specifically bind to human transthyretin (TTR). The anti-TTR antibodies or antigen-binding fragments thereof are useful, for example, in detecting TTR and in treating TTR amyloidosis in a subject.