公开(公告)号：US12042614B2

公开(公告)日：2024-07-23

申请号：US17703910

申请日：2022-03-24

申请人： Morningside Venture Investments Limited

发明人： Andrew L. Johnston ,  Michael P. Schaller ,  Bryce Peterson ,  Kevin Gelston

IPC分类号： A61M35/00 ,  A61K9/70 ,  A61M5/142 ,  A61M5/145

CPC分类号： A61M35/00 ,  A61K9/703 ,  A61M5/14248 ,  A61M5/145 ,  A61M5/1454 ,  A61M2005/14268 ,  A61M2005/14533 ,  A61M2205/103 ,  A61M2205/106 ,  A61M2205/502 ,  A61M2205/8206

摘要： A transdermal drug delivery device includes a reservoir, a transdermal membrane, a piston, a control rod, a spring, and a rotational cam. The reservoir is configured to hold a formulation. The transdermal membrane is configured to allow the formulation from the reservoir to pass therethrough. The piston is configured to move into the reservoir. The control rod is attached to the piston and includes a plurality of teeth thereon. The spring is configured to apply force to the control rod in the direction of the reservoir. The rotational cam has a first camming surface and a second camming surface that are configured to engage with the plurality of teeth. The rotational cam, when rotated, is configured to disengage the first camming surface from a first tooth of the plurality of teeth, thereby allowing the spring to advance the piston into the reservoir to expel the formulation onto the transdermal membrane.

公开(公告)号：US11285306B2

公开(公告)日：2022-03-29

申请号：US16473981

申请日：2018-01-05

申请人： Morningside Venture Investments Limited

发明人： Andrew L. Johnston ,  Michael P. Schaller ,  Bryce Peterson ,  Kevin Gelston

IPC分类号： A61M35/00 ,  A61K9/70 ,  A61M5/142 ,  A61M5/145

摘要： A transdermal drug delivery device includes a reservoir, a transdermal membrane, a piston, a control rod, a spring, and a rotational cam. The reservoir is configured to hold a formulation. The transdermal membrane is configured to allow the formulation from the reservoir to pass therethrough. The piston is configured to move into the reservoir. The control rod is attached to the piston and includes a plurality of teeth thereon. The spring is configured to apply force to the control rod in the direction of the reservoir. The rotational cam has a first camming surface and a second camming surface that are configured to engage with the plurality of teeth. The rotational cam, when rotated, is configured to disengage the first camming surface from a first tooth of the plurality of teeth, thereby allowing the spring to advance the piston into the reservoir to expel the formulation onto the transdermal membrane.