公开(公告)号：US08841296B2

公开(公告)日：2014-09-23

申请号：US13260720

申请日：2010-03-23

申请人： Mukund Vinayak Deshpande ,  Sunita Ranjan Deshpande ,  Fazal Shirazi ,  Preeti Madhukar Chaudhary ,  Nelavelli Malleswara Rao ,  Baidyanath Mohanty ,  Nageshwar Nath Sharma ,  Anand Kumar Bachhawat ,  Ganesan Kaliannan ,  Sanjoy Paul ,  Raj Kumar ,  Bommena Vittal Rao ,  Bhimrao Bodhanrao Gawali ,  Vaddu Venkata Narayana Reddy ,  Jhillu Singh Yadav

发明人： Mukund Vinayak Deshpande ,  Sunita Ranjan Deshpande ,  Fazal Shirazi ,  Preeti Madhukar Chaudhary ,  Nelavelli Malleswara Rao ,  Baidyanath Mohanty ,  Nageshwar Nath Sharma ,  Anand Kumar Bachhawat ,  Ganesan Kaliannan ,  Sanjoy Paul ,  Raj Kumar ,  Bommena Vittal Rao ,  Bhimrao Bodhanrao Gawali ,  Vaddu Venkata Narayana Reddy ,  Jhillu Singh Yadav

IPC分类号： A01N43/90 ,  C07D491/113 ,  A01P3/00 ,  C07D498/20

CPC分类号： C07D498/20

摘要： This invention provides novel substituted 1,4-dioxa-8-azaspiro[4,5]decane compounds of the general formula (1), wherein R1 is selected from phenethyl, 4,6-dimethoxypyrimidin-2-yl and (2-chloro-5-thiazolyl)methyl and R2 is selected from the group consisting of hydroxy, 4-bromo-2-chlorophenoxy, morpholin-4-yl, (2-chloro-5-thiazolyl)methyloxy, benzyloxy, phenylsulfanyl, benzotriazol and 5-chloro-2-fluoroanilino. The present invention also relates to a process for the preparation of novel substituted 1,4-dioxa-8-azaspiro[4,5]decanes of general formula (1). The novel substituted 1,4-dioxa-8-azaspiro[4,5]decane of general formula (1) has fungicidal activity.

摘要翻译： 本发明提供了通式（1）的新的取代的1,4-二氧杂-8-氮杂螺[4,5]癸烷化合物，其中R 1选自苯乙基，4,6-二甲氧基嘧啶-2-基和（2-氯 -5-噻唑基）甲基，R 2选自羟基，4-溴-2-氯苯氧基，吗啉-4-基，（2-氯-5-噻唑基）甲氧基，苄氧基，苯硫基，苯并三唑和5- 氯-2-氟苯胺基。 本发明还涉及制备通式（1）的新的取代的1,4-二氧杂-8-氮杂螺[4,5]癸烷的方法。 通式（1）的新型取代的1,4-二氧杂-8-氮杂螺[4,5]癸烷具有杀真菌活性。

公开(公告)号：US20120225877A1

公开(公告)日：2012-09-06

申请号：US13260720

申请日：2010-03-23

申请人： Mukund Vinayak Deshpande ,  Sunita Ranjan Deshpande ,  Fazal Shirazi ,  Preeti Madhukar Chaudhary ,  Nelavelli Malleswara Rao ,  Baidyanath Mohanty ,  Nageshwar Nath Sharma ,  Anand Kumar Bachhawat ,  Ganesan Kaliannan ,  Sanjoy Paul ,  Raj Kumar ,  Bommena Vittal Rao ,  Bhimrao Bodhanrao Gawali ,  Vaddu Venkata Narayana Reddy ,  Jhillu Singh Yadav

发明人： Mukund Vinayak Deshpande ,  Sunita Ranjan Deshpande ,  Fazal Shirazi ,  Preeti Madhukar Chaudhary ,  Nelavelli Malleswara Rao ,  Baidyanath Mohanty ,  Nageshwar Nath Sharma ,  Anand Kumar Bachhawat ,  Ganesan Kaliannan ,  Sanjoy Paul ,  Raj Kumar ,  Bommena Vittal Rao ,  Bhimrao Bodhanrao Gawali ,  Vaddu Venkata Narayana Reddy ,  Jhillu Singh Yadav

IPC分类号： A01N43/90 ,  A01P3/00 ,  C07D491/113

CPC分类号： C07D498/20

摘要： This invention relates provides novel substituted 1,4-dioxa-8-azaspiro[4,5]decane of general formula (1), wherein R1 is selected from phenethyl, 4,6-dimethoxypyrimidin-2-yl and (2-chloro-5-thiazolyl)methyl and R2 is selected from the group consisting of hydroxy, 4-bromo-2-chlorophenoxy, morpholin-4-yl, (2-chloro-5-thiazolyl)methyloxy, benzyloxy, phenylsulfanyl, benzotriazol-1-yl and 5-chloro-2-fluoroanilino. The present invention also relates to a process for the preparation of novel substituted 1,4-dioxa-8-azaspiro[4,5]decanes of general formula (1). The novel substituted 1,4-dioxa-8-azaspiro[4,5]decane of general formula (1) has fungicidal activity.

摘要翻译： 本发明涉及通式（1）的新的取代的1,4-二氧杂-8-氮杂螺[4,5]癸烷，其中R1选自苯乙基，4,6-二甲氧基嘧啶-2-基和（2-氯 - 5-噻唑基）甲基，R 2选自羟基，4-溴-2-氯苯氧基，吗啉-4-基，（2-氯-5-噻唑基）甲氧基，苄氧基，苯硫基，苯并三唑-1-基 和5-氯-2-氟苯胺基。 本发明还涉及制备通式（1）的新的取代的1,4-二氧杂-8-氮杂螺[4,5]癸烷的方法。 通式（1）的新型取代的1,4-二氧杂-8-氮杂螺[4,5]癸烷具有杀真菌活性。