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1.发明授权Benzo-1,4-diazepin-2-one derivatives as phosphodiesterase PDE2 inhibitors, preparation and therapeutic use thereof 失效苯并-1,4-二氮杂-2-酮衍生物作为磷酸二酯酶PDE2抑制剂，其制备和治疗用途公开(公告)号：US07410963B2
公开(公告)日：2008-08-12
申请号：US10582131
申请日：2004-12-23
申请人： Mustapha Abarghaz , Stefano Biondi , Jérôme Duranton , Emmanuelle Limanton , Cesare Mondadori , Patrick Wagner
发明人： Mustapha Abarghaz , Stefano Biondi , Jérôme Duranton , Emmanuelle Limanton , Cesare Mondadori , Patrick Wagner
IPC分类号： C07D243/24 , C07D413/04 , A61K31/5513
CPC分类号： C07D405/04 , C07D243/24
摘要： The invention relates to compounds having PDE2 inhibitory activities, as well as therapeutic methods by administering said compounds, in particular for treating various diseases of the central or peripheral nervous system. It further deals with pharmaceutical compositions comprising said compounds and methods for preparing said compounds.
摘要翻译： 本发明涉及具有PDE2抑制活性的化合物，以及通过施用所述化合物，特别是用于治疗中枢或周围神经系统的各种疾病的治疗方法。 它还涉及包含所述化合物的药物组合物和制备所述化合物的方法。
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2.发明申请Benzo-1,4-diazepin-2-one derivatives as phosphodiesterase pde2 inhibitors, preparation and therapeutic use thereof 失效苯并-1,4-二氮杂-2-酮衍生物作为磷酸二酯酶pde2抑制剂，其制备和治疗用途公开(公告)号：US20070123519A1
公开(公告)日：2007-05-31
申请号：US10582131
申请日：2004-12-23
申请人： Mustapha Abarghaz , Stefano Biondi , Jerome Duranton , Emmanuelle Limanton , Cesare Mondadori , Patrick Wagner
发明人： Mustapha Abarghaz , Stefano Biondi , Jerome Duranton , Emmanuelle Limanton , Cesare Mondadori , Patrick Wagner
IPC分类号： A61K31/5513 , C07D243/14
CPC分类号： C07D405/04 , C07D243/24
摘要： The invention relates to compounds having PDE2 inhibitory activities, as well as therapeutic methods by administering said compounds, in particular for treating various diseases of the central or peripheral nervous system. It further deals with pharmaceutical compositions comprising said compounds and methods for preparing said compounds.
摘要翻译： 本发明涉及具有PDE2抑制活性的化合物，以及通过施用所述化合物，特别是用于治疗中枢或周围神经系统的各种疾病的治疗方法。 它还涉及包含所述化合物的药物组合物和制备所述化合物的方法。
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