公开(公告)号：US11726083B2

公开(公告)日：2023-08-15

申请号：US16957625

申请日：2018-12-26

申请人： Myoridge Co. Ltd.

发明人： Shinichi Sueta ,  Itsunari Minami ,  Tomoko Kasahara ,  Kentaro Ishida ,  Naohiro Makita

IPC分类号： C12Q1/02 ,  G01N33/50 ,  G01N33/84

CPC分类号： G01N33/5061 ,  G01N33/84 ,  G01N2500/10

摘要： A method for testing drug response of a cardiomyocyte, the method comprising: testing a response of the cardiomyocyte to an added drug in a culture medium under a condition in which a distance from a liquid surface of the culture medium to a bottom surface of a culture vessel contacted by the cardiomyocyte is 5.0 mm or less; or testing a response of the cardiomyocyte to an added drug immediately after placing the cardiomyocyte in a culture medium under a condition in which a distance from a liquid surface of the culture medium to a bottom surface of a culture vessel contacted by the cardiomyocyte is 5.0 mm or less.

公开(公告)号：US20230408495A1

公开(公告)日：2023-12-21

申请号：US18337884

申请日：2023-06-20

申请人： MYORIDGE CO. LTD.

发明人： Shinichi Sueta ,  Itsunari Minami ,  Tomoko Kasahara ,  Kentaro Ishida ,  Naohiro Makita

IPC分类号： G01N33/50 ,  G01N33/84

CPC分类号： G01N33/5061 ,  G01N33/84 ,  G01N2500/10

摘要： A method for testing drug response of a cardiomyocyte, the method comprising: testing a response of the cardiomyocyte to an added drug in a culture medium under a condition in which a distance from a liquid surface of the culture medium to a bottom surface of a culture vessel contacted by the cardiomyocyte is 5.0 mm or less; or testing a response of the cardiomyocyte to an added drug immediately after placing the cardiomyocyte in a culture medium under a condition in which a distance from a liquid surface of the culture medium to a bottom surface of a culture vessel contacted by the cardiomyocyte is 5.0 mm or less.

公开(公告)号：US20210363474A1

公开(公告)日：2021-11-25

申请号：US17251112

申请日：2019-07-04

申请人： MYORIDGE CO. LTD.

发明人： Itsunari Minami ,  Shinichi Sueta ,  Toyomi Nakamura ,  Saori Fujikawa ,  Maiko Minatohara

IPC分类号： C12M3/00 ,  C12M3/04 ,  C12M1/42 ,  C12N5/077

摘要： A method for producing a cell sheet, the method including subjecting animal cells dispersed in a culture medium to a suspension culture while gathering the animal cells toward the center of the culture medium, to form a cell sheet floating in the culture medium.

公开(公告)号：US20210372993A1

公开(公告)日：2021-12-02

申请号：US16957625

申请日：2018-12-26

申请人： Myoridge Co. Ltd.

发明人： Shinichi Sueta ,  Itsunari Minami ,  Tomoko Kasahara ,  Kentaro Ishida ,  Naohiro Makita

IPC分类号： G01N33/50 ,  G01N33/84

摘要： A method for testing drug response of a cardiomyocyte, the method comprising: testing a response of the cardiomyocyte to an added drug in a culture medium under a condition in which a distance from a liquid surface of the culture medium to a bottom surface of a culture vessel contacted by the cardiomyocyte is 5.0 mm or less; or testing a response of the cardiomyocyte to an added drug immediately after placing the cardiomyocyte in a culture medium under a condition in which a distance from a liquid surface of the culture medium to a bottom surface of a culture vessel contacted by the cardiomyocyte is 5.0 mm or less.