公开(公告)号：US20230390411A1

公开(公告)日：2023-12-07

申请号：US18037884

申请日：2022-01-28

申请人： NANJING CHEMPION BIOTECHNOLOGY CO., LTD.

发明人： Jian Chen ,  Haibo Zhao ,  Rong Gu

IPC分类号： A61K47/68 ,  A61K47/60 ,  A61K31/35 ,  A61P35/00 ,  A61K31/4741

CPC分类号： A61K47/68031 ,  A61K47/60 ,  A61K31/35 ,  A61P35/00 ,  A61K31/4741

摘要： A compound of formula (I), or a tautomer, a stereoisomer or a pharmaceutically acceptable salt thereof. The compound represented by formula (I) or the tautomer, the stereoisomer or the pharmaceutically acceptable salt thereof, as a novel linker compound, can be used for preparing an ADC medicament with a high DAR value. The present invention also relates to an ADC medicament prepared from the linker.