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公开(公告)号：US20210378975A1
公开(公告)日：2021-12-09
申请号：US16764551
申请日：2019-04-03
Inventor： Lele LI , Congli WANG , Zhenghan DI
IPC: A61K9/51
Abstract: The present application relates to a metal-nucleic acid nanoparticle which is a nanoparticle having a spherical structure formed by assembly of metal ions with nucleic acids via coordination. The preparation thereof is mixing a metal ion solution with a nucleic acid solution to obtain a mixture followed by vortex, heating, centrifugation, washing with water and resuspension to obtain the metal-nucleic acid nanoparticles.
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