专利检索 ap:("NATIONAL DONG HWA UNIVERSITY") AND inv:"Ying-Chi Du" 第 1 页

1.

发明授权
Scalarane sesterterpenoid, pharmaceutical composition and topoisomerase II and Hsp90 inhibitor for treating cancer, and use and preparation method thereof 有权

公开(公告)号：US10314847B2

公开(公告)日：2019-06-11

申请号：US15676102

申请日：2017-08-14

申请人： NATIONAL DONG HWA UNIVERSITY

发明人： Mei-Chin Lu , Ping-Jyun Sung , Jui-Hsin Su , Kuei-Hung Lai , Yi-Chang Liu , Ying-Chi Du , Yu-Ming Hsu , Ming-Kai Weng , Fu-Wen Kuo

IPC分类号： A61K31/56 , A61K35/655 , A61K31/122

摘要： The present invention discloses scalarane sesterterpenoids represented by formula (I) and meroditerpenoid represented by formula (II), which are extracted from Carteriospongia sp. sponge: where R1 is —CH3 or —C2H5. The compounds of formula (I) can be used to be an anticancer, act as an inhibitor targeting to topoisomerase II and hsp90 and a pharmaceutical composition for anticancer.

2.

发明申请
SCALARANE SESTERTERPENOID, PHARMACEUTICAL COMPOSITION AND TOPOISOMERASE II AND Hsp90 INHIBITOR FOR TREATING CANCER, AND USE AND PREPARATION METHOD THEREOF 审中-公开

公开(公告)号：US20180271879A1

公开(公告)日：2018-09-27

申请号：US15676102

申请日：2017-08-14

申请人： NATIONAL DONG HWA UNIVERSITY

发明人： Mei-Chin Lu , Ping-Jyun Sung , Jui-Hsin Su , Kuei-Hung Lai , Yi-Chang Liu , Ying-Chi Du , Yu-Ming Hsu , Ming-Kai Weng , Fu-Wen Kuo

IPC分类号： A61K31/56 , A61K31/122 , A61K35/655

CPC分类号： A61K31/56 , A61K31/122 , A61K35/655

摘要： The present invention discloses scalarane sesterterpenoids represented by formula (I) and meroditerpenoid represented by formula (II), which are extracted from Carteriospongia sp. sponge: where R1 is —CH3 or —C2H5. The compounds of formula (I) can be used to be an anticancer, act as an inhibitor targeting to topoisomerase II and hsp90 and a pharmaceutical composition for anticancer.