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公开(公告)号：US20190175684A1
公开(公告)日：2019-06-13
申请号：US16326120
申请日：2017-08-16
Inventor： Michiko FUKUDA , Motohiro NONAKA
Abstract: The present invention provides a peptide comprising the amino acid sequence of any of the formulas (I-(III) below: (I) an amino acid sequence of (X1)[D]P[D](X2)[D] wherein X1 is W or F, X2 is S or T, and each amino acid symbol immediately followed by symbol [D] is a D form of the amino acid, (II) an amino acid sequence of P[D]T[D](X)n F[D] wherein (X)n is any amino acid in the number of n selected independently of each other, n is an integer of 0-4, and the symbol [D] is as defined above, (III) an amino acid sequence that is a Retro-inverso of the amino acid sequence of any of the aforementioned (I) and the aforementioned (II); and a conjugate containing the peptide and a functional part.
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公开(公告)号：US20200323943A1
公开(公告)日：2020-10-15
申请号：US16912688
申请日：2020-06-25
Inventor： Michiko FUKUDA , Motohiro NONAKA
IPC: A61K38/03 , A61K38/06 , A61K49/04 , A61K49/14 , A61P35/00 , A61K49/06 , C07K14/00 , A61K45/00 , C07K19/00 , C07K5/08 , C07K7/06 , C07K5/10 , A61K47/64 , A61K49/08
Abstract: The present invention provides a peptide comprising the amino acid sequence of any of the formulas (I)-(III) below:(I) an amino acid sequence of (X1) [D] P [D] (X2) [D] wherein X1 is W or F, X2 is S or T, and each amino acid symbol immediately followed by symbol [D] is a D form of the amino acid, (II) an amino acid sequence of P[D]T[D] (X)n F[D] wherein (X)n is any amino acid in the number of n selected independently of each other, n is an integer of 0-4, and the symbol [D] is as defined above, (III) an amino acid sequence that is a Retro-inverso of the amino acid sequence of any of the aforementioned (I) and the aforementioned (II); and a conjugate containing the peptide and a functional part.
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