公开(公告)号：US20230041921A1

公开(公告)日：2023-02-09

申请号：US17789086

申请日：2019-12-31

Applicant: National Institute of Technology Rourkela

Inventor： Devendra VERMA ,  Sabir HOSSAIN

IPC: A61L24/04 ,  A61L24/00

Abstract: A polyelectrolyte complex includes nanofibers. The nanofibers include at least one polycationic component and at least one polyanionic component. The nanofibers have a diameter in a range of 20-100 nm. A process for preparing the complex, a method of using the complex, a kit which includes the complex, and a method of inhibiting loss of blood from a wound site by applying the complex to the wound site are also provided.

公开(公告)号：US20220193115A1

公开(公告)日：2022-06-23

申请号：US17604264

申请日：2020-04-17

Applicant: NATIONAL INSTITUTE OF TECHNOLOGY ROURKELA

Inventor： Devendra VERMA ,  Sabir HOSSAIN

IPC: A61K31/722 ,  A61K9/00 ,  A61K9/70 ,  A61P7/04

Abstract: A composition has a polyanionic component comprising casein or derivatives thereof, and a polycationic component, which includes chitosan or derivatives thereof. The composition is in the form of nanofibers having a diameter in a range of 20-200 nm. Also disclosed is a process for preparing the composition and a hemostatic article with the composition. A method for inhibiting loss of blood from a hemorrhaging site involves use of the composition and the hemostatic article.