公开(公告)号：US20150292037A1

公开(公告)日：2015-10-15

申请号：US14749289

申请日：2015-06-24

Applicant: NATIONAL UNIVERSITY CORPORATION AKITA UNIVERSITY

Inventor： Satoru MOTOYAMA ,  Masatomo MIURA ,  Junichi OGAWA

IPC: C12Q1/68

CPC classification number: C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/118 ,  C12Q2600/156 ,  C12Q2600/158

Abstract: The objective of the present invention is to provide a method and a means of rapidly and reliably detecting lymph node metastasis in cancer or the risk of lymph node metastasis. Specifically, the present invention provides a method and a rapid determination kit for detecting lymph node metastasis in cancer or its risk by identifying a certain genetic polymorphism of the human CRP gene, and it is clinically significant in determining the treatment strategy, because effective prediction/determination can be made regarding lymph node metastasis, which is an important phenomenon in cancer progression.

Abstract translation: 本发明的目的是提供一种快速可靠地检测癌症淋巴结转移或淋巴结转移风险的方法和手段。 具体地说，本发明提供了一种用于通过鉴定人类CRP基因的某些遗传多态性来检测癌症中的淋巴结转移或其风险的方法和快速测定试剂盒，并且在确定治疗策略方面具有临床意义，因为有效的预测/ 可以确定淋巴结转移，这是癌症进展中的重要现象。