公开(公告)号：US20220133851A1

公开(公告)日：2022-05-05

申请号：US17360870

申请日：2021-06-28

Applicant: NEOGENTC CORP.

Inventor： Sun Hee Heo ,  Gyungyub Gong ,  Hee Jin Lee

IPC: A61K38/17 ,  A61K35/17 ,  G01N33/50 ,  C12N5/0783

Abstract: The present invention relates to an immunopotentiating or anticancer activity-augmenting composition comprising MAL-expressed, stem cell like memory T cells as an active ingredient. According to the present invention, myelin and lymphocyte (MAL) augments the differentiation, viability, and activity of stem cell like memory cells (Tscm) and MAL-expressed Tscm can be utilized in an immunopotentiating or anticancer activity-augmenting composition. MAL can be advantageously used in a composition for cancer immunotherapy, a composition for induction of Tscm differentiation, a method for screening a cancer immunotherapy agent, a method for screening a Tscm differentiation inducing agent, etc.