专利检索 ap:("NIPPON SHINYAKU CO., LTD." OR "Kawasaki Gakuen Educational Foundation") AND inv:"Seigo Nagata" 第 1 页

1.

发明授权
Antisense nucleic acid for treating amyotrophy 有权

公开(公告)号：US10563199B2

公开(公告)日：2020-02-18

申请号：US15759305

申请日：2016-09-16

申请人： NIPPON SHINYAKU CO., LTD. , Kawasaki Gakuen Educational Foundation

发明人： Shinichiro Nakagawa , Seigo Nagata , Yoshihide Sunada , Yutaka Ohsawa , Shin-ichiro Nishimatsu

IPC分类号： C12N15/113

摘要： There has been a demand for a novel antisense nucleic acid or the like capable of inhibiting myostatin at the mRNA level. The present invention provides a specific antisense oligomer which allows exon 2 skipping in the myostatin gene or induces degradation of mRNA of the myostatin gene.