公开(公告)号：US20230338661A1

公开(公告)日：2023-10-26

申请号：US18025698

申请日：2021-09-10

Applicant: NIPRO CORPORATION

Inventor： Ryo OGINO ,  Mitsuru HASEGAWA ,  Yuma SHIRAISHI

IPC: A61M5/28 ,  A61M5/19 ,  A61M5/315

CPC classification number: A61M5/28 ,  A61M5/19 ,  A61M5/31513

Abstract: A pre-filled syringe includes a tubular container, a front end gasket, a rear end gasket, an intermediate gasket, a medicine, a liquid medicine, and a plunger. The tubular container has a barrel and a nozzle portion. The barrel has an inner peripheral surface and a protruding inner side surface. A groove is formed in an outer peripheral surface of the intermediate gasket. The front end gasket has a rear-end pressure-contact portion. The nozzle portion has an accommodation portion. The accommodation portion has a bottom wall, a peripheral wall, and a supporting portion. The rear-end pressure-contact portion is in pressure contact with the inner peripheral surface of the barrel in an abutment state in which the liquid medicine is introduced in the front chamber and the front end portion of the front end gasket is in abutment with the supporting portion.

公开(公告)号：US20170119976A1

公开(公告)日：2017-05-04

申请号：US15129322

申请日：2015-02-12

Applicant: NIPRO CORPORATION

Inventor： Mitsuru HASEGAWA

IPC: A61M5/32

Abstract: A syringe includes a barrel, a plunger, an injection needle, and an injection needle safety instrument. The injection needle safety instrument has a base portion fixed to the barrel, a cover portion which can cover a pointed end of a needle tube of the injection needle, and a hinge portion which pivotably couples the base portion and the cover portion. The cover portion is constructed to be pivotable between a first position at which the cover portion is held to the base portion as a first locked portion is locked by a locking portion of the base portion and a second position at which the cover portion covers the pointed end of the needle tube and is held to the injection needle as a second locked portion is locked to the same. The cover portion is tilted toward the barrel in the first position.

公开(公告)号：US20230364345A1

公开(公告)日：2023-11-16

申请号：US18025716

申请日：2021-09-10

Applicant: NIPRO CORPORATION

Inventor： Ryo OGINO ,  Mitsuru HASEGAWA

IPC: A61M5/315 ,  A61M5/19

CPC classification number: A61M5/31511 ,  A61M5/19

Abstract: A pre-filled syringe includes a tubular container, a front end gasket, a rear end gasket, an intermediate gasket, and a plunger. The tubular container has an inner peripheral surface, a protruding inner side surface, and a receiving surface. A groove is formed in an outer peripheral surface of the intermediate gasket. The plunger has a connection portion, a pushing portion, and a guide rib. The protruding inner side surface is formed at a position facing the pushing portion in a pushing completion state. The guide rib is provided with a recess. A rear end portion of the recess is located rearward with respect to a rear end portion of the protruding inner side surface in the pushing completion state.

公开(公告)号：US20230159233A1

公开(公告)日：2023-05-25

申请号：US17295694

申请日：2019-09-27

Applicant: NIPRO CORPORATION

Inventor： Mitsuru HASEGAWA

IPC: B65D43/22 ,  B65D43/16

CPC classification number: B65D43/22 ,  B65D43/162

Abstract: A package includes a first side, a second side and a hinge. As the first side and the second side pivot around the hinge, the first side and the second side make transition between a closed state and an opened state. The first side includes a first fitting portion in a projecting shape, a rigid portion provided in a partial section on a line that goes around the first fitting portion, and a first weak portion provided in a remaining section on the line that goes around the first fitting portion and being lower in rigidity than the rigid portion. The second side includes a second fitting portion in a recessed shape and fitted to the first fitting portion in the closed state and a second weak portion provided on a line that goes around the second fitting portion and being lower in rigidity than the rigid portion.

公开(公告)号：US20170000954A1

公开(公告)日：2017-01-05

申请号：US15039776

申请日：2014-11-05

Applicant: NIPRO CORPORATION

Inventor： Mitsuru HASEGAWA ,  Minoru HONDA

IPC: A61M5/315 ,  A61M5/19 ,  A61M5/32 ,  A61M5/28

Abstract: A pre-filled syringe includes: a cylindrical container, a front end-side gasket; a rear end-side gasket; an intermediate gasket partitioning an inside of the cylindrical container into a front chamber and a rear chamber; a plunger; a medical drug contained in the front chamber, and a liquid drug contained in the rear chamber. In the state where the plunger is pushed in, a bypass portion included in the cylindrical container faces a groove portion provided in the intermediate gasket, thereby allowing communication between the front chamber and the rear chamber therethrough, so that the medical drug and the liquid drug are mixed, and a liquid mixture is discharged. The pre-filled syringe further includes a movement limiting mechanism for limiting movement of the plunger such that a tail end of the rear end-side gasket does not reach the bypass portion.

Abstract translation: 预填充注射器包括：圆柱形容器，前端侧衬垫; 后端侧垫圈; 将所述圆筒形容器的内部分隔成前室和后室的中间垫圈; 柱塞 包含在前室中的医药，以及容纳在后室中的液体药物。 在柱塞被推入的状态下，包括在圆筒形容器中的旁路部分面向设置在中间垫圈中的槽部分，从而允许前室和后室之间通过其间的连通，使得药物和液体药物 混合，排出液体混合物。 预填充注射器还包括用于限制柱塞的移动的移动限制机构，使得后端侧垫圈的尾端未到达旁路部分。