NOVEL POLY(ETHYLENE GLYCOL) DERIVATIVE AND PROTEIN-ADSORPTION INHIBITOR

    公开(公告)号:US20200271642A1

    公开(公告)日:2020-08-27

    申请号:US16645862

    申请日:2018-08-28

    申请人: NOF Corporartion

    摘要: A compound is provided which is effectively adsorbed to a substrate surface, such as an immune reaction vessel, has extremely high protein adsorption inhibitory effect that inhibits non-specific adsorption of protein or the like, and has excellent washability to retain the inhibitory effect before and after washing operation of the substrate. Also provided are a protein adsorption inhibitor using the compound, a phosphorylcholine-modified substrate, and a method for inhibiting protein adsorption. The compound is a phosphorylcholine group-containing polyethylene glycol derivative represented by formula (1). The method for inhibiting protein adsorption of the present invention includes the step of forming an adsorbed layer of the derivative on a substrate surface.