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公开(公告)号:US12194437B2
公开(公告)日:2025-01-14
申请号:US18426149
申请日:2024-01-29
Inventor: Yingqin Wu , Rong Ma , Yanhong Liu , Longmiao Yuan , Zhiyu Wang , Lantian Xing , Yan Liu , Yongxin Chen , Chuntao Tian
Abstract: A preparation method of a molecularly imprinted polymer (MIP) for separation and concentration of 4-methylsterane compounds is provided. A template molecule, a functional monomer, a porogen, an initiator and a cross-linking agent are mixed and subjected to polymerization to prepare a polymer with the template molecule, which is then treated to remove the template molecule, so as to give the desired MIP. The template molecule is β-sitosterol or deoxycholic acid. The obtained molecularly imprinted polymer has multiple stable hole structures and binding sites inside, and has memory and recognition functions for the 4-methylsterane compounds, exhibiting excellent specific adsorption performance. The MIP can contribute to the accurate identification of correlation between depositional environment and maturity of crude oils or source rocks. A molecularly imprinted polymer prepared by such method, a chromatographic column and an application thereof are also provided.