公开(公告)号：US20190388428A1

公开(公告)日：2019-12-26

申请号：US16478704

申请日：2018-01-18

Applicant: NOVARTIS AG

Inventor： Miloud Achour ,  Brumo Galli ,  Edgar John ,  Michael Juhnke ,  Dragutin Knezic ,  Vishal Shamji Koradia ,  Rita Ramos

IPC: A61K31/5355 ,  A61K31/496 ,  A61K9/48 ,  A61K47/26 ,  A61K47/38

Abstract: The present invention relates to a pharmaceutical composition comprising an oxazine derivative BACE-1 inhibitor, a process for the preparation thereof, and its use in the treatment or prevention of Alzheimer's disease.