公开(公告)号：US11066469B2

公开(公告)日：2021-07-20

申请号：US16897935

申请日：2020-06-10

Applicant: NOVARTIS AG

Inventor： John Louis Diener ,  Lars Gadtke ,  Felix Hartlepp ,  Kathrin Ladetzki-Baehs ,  Michael Romanowski ,  Cesare Russo ,  Xenia Wezler

IPC: C07K16/28 ,  A61K39/395 ,  A61P9/00 ,  A61P13/12 ,  C07K14/72 ,  A61K45/06 ,  A61K39/00 ,  C07K14/58

Abstract: This disclosure relates to anti-Natriuretic Peptide Receptor 1 (NPR1) antibodies including agonist antibodies which are able to activate the NPR1 receptor, pharmaceutical compositions comprising the same, and methods of treatment comprising the same.

公开(公告)号：US20200377603A1

公开(公告)日：2020-12-03

申请号：US16799509

申请日：2020-02-24

Applicant: Novartis AG

Inventor： Feng Cong ,  Seth Ettenberg ,  Felix Hartlepp ,  Ingo Markus Klagge

IPC: C07K16/28 ,  A61P35/00

Abstract: The present invention relates to antibodies targeting LRP6 and compositions and methods of use thereof.