公开(公告)号：US20200306198A1

公开(公告)日：2020-10-01

申请号：US16652107

申请日：2018-09-28

Applicant: NOVARTIS AG

Inventor： Florian Beck ,  Hans de Waard ,  Sarah Gold ,  Stefan Hirsch ,  David Hook ,  Nikhil Kavimandan ,  Markus Krumme ,  Steffen Lang ,  Detlef Moll ,  Siddharthya Mujumdar ,  Anh-Thu Nguyen-Trung ,  Joerg Ogorka ,  Norbert Rasenack ,  Raphael Tobler ,  Patrick Tritschler

IPC: A61K9/48

Abstract: A formulation for injection molding of a pharmaceutical carrier comprises 43.5-97% (w/w) of one or more polyethylene oxide polymer having a weight average molecular weight of MW 94,000-188,000; and optionally one or more excipients.

公开(公告)号：US20200246272A1

公开(公告)日：2020-08-06

申请号：US16652088

申请日：2018-09-28

Applicant: NOVARTIS AG

Inventor： Florian Beck ,  Hans de Waard ,  Sarah Gold ,  Stefan Hirsch ,  David Hook ,  Nikhil Kavimandan ,  Markus Krumme ,  Steffen Lang ,  Detlef Moll ,  Siddharthya Mujumdar ,  Anh-Thu Nguyen-Trung ,  Joerg Ogorka ,  Norbert Rasenack ,  Raphael Tobler ,  Patrick Tritschler

IPC: A61K9/48

Abstract: A pharmaceutical carrier (20) comprises a lid part (22) and a bottom part (24), wherein at least one of the lid part (22) and the bottom part (24) has a first wall section (26, 30) with a thickness of 180-250 μm, preferably 185-225 μm, even more preferably 190-220 μm, and most preferably about 215 μm, and a second wall section (28, 32) with a thickness of 350-450 μm, preferably 375-425 μm, more preferably 390-410 μm, and most preferably about 400 μm. The first wall section (26) of the lid part (22) defines an entire top portion of the lid part (22). Alternatively or additionally thereto, the first wall section (30) of the bottom part (24) defines an entire bottom portion of the bottom part (24).