公开(公告)号：US11492402B2

公开(公告)日：2022-11-08

申请号：US16601070

申请日：2019-10-14

Applicant: NOVARTIS AG

Inventor： Verena Brand ,  Dominik Feuerbach ,  Fabrizio Gasparini ,  Nathalie George ,  Eveline Schaadt ,  Derya Shimshek ,  Honnappa Srinivas ,  Markus Waldhuber ,  Rainer Wilcken

IPC: C07K16/28 ,  A61P25/28 ,  A61K39/395 ,  A61K39/00 ,  C12N7/00 ,  C12N15/70

Abstract: The present invention provides antibodies that bind to and stabilize human Triggering Receptor Expressed on Myeloid cells 2 (TREM2) protein and methods of using these antibodies.