公开(公告)号：US20220289732A1

公开(公告)日：2022-09-15

申请号：US17633495

申请日：2020-08-07

Applicant: NOVARTIS AG

Inventor： Lichao FANG ,  Zhenting GAO ,  Xiangqing JIANG ,  Kevin Kun Chin LIU ,  Sing Yeung Frankie MAK ,  Counde OYANG ,  Ce WANG ,  Tao WANG ,  Jianping WU ,  Wu YINGMING ,  Qitao XIAO

IPC: C07D413/14 ,  C07D401/14 ,  C07D405/14 ,  C07D491/107 ,  C07D401/06 ,  C07D498/04 ,  C07D471/04 ,  C07D401/04

Abstract: The present invention provides compounds of Formula (I) or a pharmaceutically acceptable salt thereof; (I) which are inhibitors of WDR5. The present invention also provides pharmaceutical compositions comprising such compounds, compositions comprising such compounds with an additional therapeutic agent and the therapeutic uses of such compounds.