公开(公告)号：US11878973B2

公开(公告)日：2024-01-23

申请号：US17824407

申请日：2022-05-25

申请人： NOVARTIS AG

发明人： Vincent Bordas ,  Jvan Brun ,  Markus Furegati ,  Jacques Hamon ,  Jürgen Hans-Hermann Hinrichs ,  Philipp Holzer ,  Fatma Limam ,  Henrik Möbitz ,  Sandro Nocito ,  Simone Plattner ,  Niko Schmiedeberg ,  Joseph Schoepfer ,  Ross Sinclair Strang ,  Frédéric Zecri

IPC分类号： C07D413/14 ,  C07D401/14 ,  C07D405/14

CPC分类号： C07D413/14 ,  C07D401/14 ,  C07D405/14 ,  C07B2200/13

摘要： The present invention provides a compound, or a pharmaceutically acceptable salt thereof, of formula (I):




wherein R1, R2, R3, R4, R5, R26, R27, y, R, M, W, L, V, T, Y, J, K and A are as described herein, therapeutic uses of said compounds, uses of said compounds as research chemicals, a pharmaceutical composition and combinations comprising said compounds, and methods for manufacturing the compounds of the invention.