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公开(公告)号:US20130059779A1
公开(公告)日:2013-03-07
申请号:US13664055
申请日:2012-10-30
Applicant: NOVARTIS AG
Inventor: David Jonathan GLASS , Mara FORNARO
CPC classification number: C07K14/475 , A61K38/30 , C07K14/65
Abstract: The invention relates to stabilized polypeptides having an IGF-1 sequence and an Ea peptide sequence, where the natural physiological cleavage of the Ea peptide from the IGF-1 is prevented.
Abstract translation: 本发明涉及具有IGF-1序列和Ea肽序列的稳定多肽,其中防止了来自IGF-1的Ea肽的天然生理切割。