公开(公告)号：US20220162339A1

公开(公告)日：2022-05-26

申请号：US17450122

申请日：2021-10-06

Applicant: NOVARTIS AG

Inventor： Maximilian AIGNER ,  Alexander Wolfgang KOCH ,  Markus WALDHUBER

IPC: C07K16/40 ,  C07K16/36

Abstract: The present disclosure relates to monoclonal antibodies and antigen binding fragments thereof that bind to human Factor XI and activated Factor XI (“Factor XIa”), and pharmaceutical compositions and methods of treatment comprising the same.

公开(公告)号：US20250101130A1

公开(公告)日：2025-03-27

申请号：US18655058

申请日：2024-05-03

Applicant: NOVARTIS AG

Inventor： Maximilian AIGNER ,  Alexander Wolfgang KOCH ,  Markus WALDHUBER

IPC: C07K16/40 ,  C07K16/36

Abstract: The present disclosure relates to monoclonal antibodies and antigen binding fragments thereof that bind to human Factor XI and activated Factor XI (“Factor XIa”), and pharmaceutical compositions and methods of treatment comprising the same.