专利检索 ap:("NOVEOME BIOTHERAPEUTICS, INC.") AND inv:"Larry R. BROWN" 第 1 页

1.

发明公开
SECRETOME FRACTIONS AND USES THEREOF 审中-公开

公开(公告)号：US20240066071A1

公开(公告)日：2024-02-29

申请号：US18036815

申请日：2021-11-16

申请人： NOVEOME BIOTHERAPEUTICS, INC.

发明人： Howard C. WESSEL , Larry R. BROWN , Ziv Z. KIRSHNER

IPC分类号： A61K35/50 , C12N5/073 , A61P25/00

CPC分类号： A61K35/50 , C12N5/0605 , A61P25/00

摘要： Molecular weight fractions of a conditioned medium of cultured amnion-derived multipotent progenitor cells, i.e., secretome fractions, and methods of processing a secretome such that it is separated into molecular weight fractions. Uses of the molecular weight secretome fractions to stimulate Schwann cell proliferation, promote neuroprotection, reduce retinal ganglion cell (RGC) loss, and reduce optic nerve inflammation in patients in need thereof.