公开(公告)号：US10098948B2

公开(公告)日：2018-10-16

申请号：US15018346

申请日：2016-02-08

申请人： NutriLeads B.V.

发明人： Ruud Albers ,  Jari Helin ,  Werner Klaffke ,  Jean Hypolites Koek ,  Petronella Anna Kreijveld ,  Jari Natunen ,  Erwin Werner Tareilus ,  Richardus Paulus Anton Oranje

IPC分类号： A61K31/715 ,  C08B37/00 ,  A61K39/39 ,  A23L29/30 ,  A23L5/00 ,  A23L7/00 ,  A23L33/125

摘要： Objective of the present invention is to provide polysaccharides which modulate immune response, and which can be used as ingredients in edible products or pharmaceutical compositions. The present invention provides such polysaccharides obtained from the species Camellia sinensis, which comprise a rhamnogalacturonan-I core, and wherein the molar ratio of galacturonyl acid residues to rhamnosyl residues in the backbone of the polysaccharide is close to 1:1. The present invention also provides edible products or pharmaceutical compositions containing such polysaccharides, in order to modulate immune response.

公开(公告)号：US10449249B2

公开(公告)日：2019-10-22

申请号：US16054849

申请日：2018-08-03

申请人： NUTRILEADS B.V.

发明人： Ruud Albers ,  Jari Helin ,  Werner Klaffke ,  Jean Hypolites Koek ,  Petronella Anna Kreijveld ,  Jari Natunen ,  Erwin Werner Tareilus ,  Richardus Paulus Anton Oranje

IPC分类号： A61K31/715 ,  C08B37/00 ,  A61K39/39 ,  A23L29/30 ,  A23L5/00 ,  A23L7/00 ,  A23L33/125

摘要： Objective of the present invention is to provide polysaccharides which modulate immune response, and which can be used as ingredients in edible products or pharmaceutical compositions. The present invention provides such polysaccharides obtained from the species Camellia sinensis, which comprise a rhamnogalacturonan-I core, and wherein the molar ratio of galacturonyl acid residues to rhamnosyl residues in the backbone of the polysaccharide is close to 1:1. The present invention also provides edible products or pharmaceutical compositions containing such polysaccharides, in order to modulate immune response.